EEF2K antibody

Catalog No. ABIN6569898

Product Details anti-EEF2K Antibody

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EEF2K antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human EEF2K

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EEF2K

Target: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Alternative Name: EEF2K (EEF2K Products)

Synonyms: HSU93850 antibody, eEF-2K antibody, C86191 antibody, SMEF2K antibody, eEF-2 kinase antibody, cb365 antibody, fa04b08 antibody, wu:fa04b08 antibody, zgc:100973 antibody, eukaryotic elongation factor 2 kinase antibody, eukaryotic elongation factor-2 kinase antibody, EEF2K antibody, Eef2k antibody, eef2k antibody, LOC101930123 antibody

Background:

Synonyms: C86191,Calcium/calmodulin dependent eukaryotic elongation factor 2,Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase,Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase,Calmodulin dependent protein kinase III,cb365,EC 2.7.11.20,eEF 2 kinase,eEF 2K,eEF-2 kinase,eEF-2K,Eef2k,EEF2K protein,EF2K,Elongation factor 2 kinase,Eukaryotic elongation factor 2 kinase,fa04b08,HSU93850,kinase eEF2K,MGC45041,SMEF2K,wu:fa04b08,zgc:100973

Background: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Molecular Weight:

Observed_MW: 110kDa

Calculated_MW: 82kDa

Gene ID: 29904

UniProt: O00418

Pathways: AMPK Signaling