CD11b antibody
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- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD11b antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Purification
- Purified
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
- Clone
- M1-70
- Isotype
- IgG2b, kappa
- Top Product
- Discover our top product ITGAM Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Matching Isotype Control: AF/LE Purified Rat IgG2b, κ Isotype Control (ABIN7469855)
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- Store at 2~8°C. Do not freeze.
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- CD11b (ITGAM Products)
- Synonyms
- CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
- Background
- Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b,CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
- Gene ID
- 16409, 3684
- UniProt
- P05555, P11215
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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