PTPN11 antibody (pTyr542) (Biotin)

Catalog No. ABIN6879140

The Biotin-conjugated Rabbit Monoclonal anti-PTPN11 antibody (Clone SN61-01) (ABIN6879140) specifically detects PTPN11 in WB, IF and ICC. The antibody is reactive with Human and Mouse samples.

Quick Overview for PTPN11 antibody (pTyr542) (Biotin) (ABIN6879140)

Target: PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PTPN11 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: SN61-01

Product Details anti-PTPN11 Antibody (Biotin)

Binding Specificity: pTyr542

Purpose: Conjugated SHP2(Phospho-Y542) Rabbit mAb

Purification: Protein A affinity purified

Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Tyr542 of human SHP2.

Application Details

Application Notes: Biotin conjugated: Working with enzyme-conjugated streptavidin. ELISA: 1: 200 - 1: 1,000; Western Blot: 1: 200 - 1: 1,000; IHC/ICC: 1: 100 - 1: 500; Flow Cytometry: 1: 50 - 1: 250; IF: 1: 100 - 1: 500.

Restrictions: For Research Use only

Handling

Buffer: Liquid in PBS, 0.5 % BSA, 40 % Glycerol, 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light!

Storage: 4 °C

Storage Comment: Store at 4°C in dark for 6 months

Target Details for PTPN11

Target: PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))

Alternative Name: SHP2

Background: BPTP3 antibody CFC antibody JMML antibody METCDS antibody MGC14433 antibody NS1 antibody OTTHUMP00000166107 antibody OTTHUMP00000166108 antibody Protein tyrosine phosphatase 2 antibody Protein tyrosine phosphatase 2C antibody Protein tyrosine phosphatase non receptor type 11 antibody Protein-tyrosine phosphatase 1D antibody Protein-tyrosine phosphatase 2C antibody PTN11_HUMAN antibody PTP-1D antibody PTP-2C antibody PTP1D antibody PTP2C antibody PTPN11 antibody SAP2 antibody SH-PTP2 antibody SH-PTP3 antibody SH2 domain containing protein tyrosine phosphatase 2 antibody SHP 2 antibody SHP-2 antibody Shp2 antibody SHPTP2 antibody SHPTP3 antibody Syp antibody Tyrosine-protein phosphatase non-receptor type 11 antibody

Molecular Weight: Predicted band size: 68 kDa

Gene ID: 5781

UniProt: Q06124

Pathways: JAK-STAT Signaling, RTK Signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect