DPP4 antibody
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- Target See all DPP4 Antibodies
- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DPP4 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
- Specificity
- Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.
- No Cross-Reactivity
- Pig (Porcine), Sheep (Ovine)
- Cross-Reactivity (Details)
- Human. Rat. Does not react with Pig or Sheep.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Human T cell clone
- Clone
- 202-36
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product DPP4 Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen Only) (1-2 μg/mL for 30 minutes at RT) Optimal dilution for a specific application should be determined.
Positive_Control: YT, HEP-G2 cells and lymphocytes. Lymph nodes and tonsils.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
- Alternative Name
- DPP4 (DPP4 Products)
- Synonyms
- ADABP antibody, ADCP2 antibody, CD26 antibody, DPPIV antibody, TP103 antibody, MGC81966 antibody, MOP9.8 antibody, MOP9_8 antibody, DPP4 antibody, si:ch73-2d23.3 antibody, Cd26 antibody, Dpp-4 antibody, THAM antibody, dipeptidyl peptidase 4 antibody, dipeptidyl-peptidase 4 S homeolog antibody, prolyl oligopeptidase family protein antibody, dipeptidyl-peptidase 4 antibody, dipeptidylpeptidase 4 antibody, DPP4 antibody, dpp4.S antibody, AT5G24260 antibody, dpp4 antibody, Dpp4 antibody
- Background
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ADA-binding protein (ADABP), Adenosine deaminase complexing protein 2 (ADCP-2), Dipeptidyl peptidase 4, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase, intestinal, Dipeptidylpeptidase 4, Dipeptidylpeptidase IV, DPP4, DPPIV, Intestinal dipeptidyl peptidase, T-cell activation antigen CD26, TP103,CD26 (DPP IV / ADA-Binding Protein)
Cellular localisation: Cell Surface - Molecular Weight
- 110kDa
- Gene ID
- 1803, 368912
- UniProt
- P27487
- Pathways
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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