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beta-2 Microglobulin antibody

B2M Reactivity: Human FACS, IF Host: Mouse Monoclonal 246-E9-E7-same as HLA-ABC-m2 unconjugated
Catalog No. ABIN6940409
  • Target See all beta-2 Microglobulin (B2M) Antibodies
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Reactivity
    • 200
    • 52
    • 31
    • 27
    • 9
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 115
    • 109
    • 11
    • 9
    • 1
    • 1
    Mouse
    Clonality
    • 129
    • 116
    • 1
    Monoclonal
    Conjugate
    • 108
    • 33
    • 25
    • 14
    • 13
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This beta-2 Microglobulin antibody is un-conjugated
    Application
    • 126
    • 110
    • 73
    • 65
    • 59
    • 41
    • 39
    • 31
    • 26
    • 18
    • 17
    • 15
    • 13
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Specificity
    Recognizes a protein of 12 kDa, identified as beta-microglobulin. Beta--microglobulin non-covalently associates with the 44 kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. Detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
    No Cross-Reactivity
    Non-Human Primate
    Purification
    Purified by Protein A/G
    Immunogen
    Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient
    Clone
    246-E9-E7-same as HLA-ABC-m2
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product B2M Primary Antibody
  • Application Notes

    Positive Control: HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.

    Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    Alternative Name
    B2M (B2M Products)
    Synonyms
    Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
    Molecular Weight
    12kDa
    Gene ID
    567
    UniProt
    P61769
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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