BAG2 antibody

Catalog No. ABIN6989609

Product Details anti-BAG2 Antibody

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BAG2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Synthetic Peptide within N-terminal Human BAG2.

Clone: 2F9

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for BAG2

Target: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Alternative Name: BAG2 (BAG2 Products)

Synonyms: bag2 antibody, MGC89300 antibody, BAG2 antibody, ATBAG2 antibody, BCL-2-associated athanogene 2 antibody, MTG10.13 antibody, MTG10_13 antibody, BAG-2 antibody, dJ417I1.2 antibody, zgc:64195 antibody, 2610042A13Rik antibody, BC016230 antibody, BCL2 associated athanogene 2 antibody, BCL-2-associated athanogene 2 antibody, BCL2-associated athanogene 2 antibody, Bcl2-associated athanogene 2 antibody, bag2 antibody, BAG2 antibody, Bag2 antibody

Background:

Synonyms: BAG 2 antibody, BAG family molecular chaperone regulator 2 antibody, BAG-2 antibody, BAG-family molecular chaperone regulator-2 antibody, Bag2 antibody, BAG2_HUMAN antibody, BCL 2 associated athanogene 2 antibody, Bcl-2-associated athanogene 2 antibody, BCL2 associated athanogene 2 antibody, BCL2-associated athanogene 2 antibody, dJ417I1.2 (BAG family molecular chaperone regulator 2) antibody, dJ417I1.2 antibody, KIAA0576 antibody, MGC149462 antibody, OTTHUMP00000016668 antibody

Background: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq].

Gene ID: 9532

UniProt: O95816