Histone 3 antibody (meArg2)
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- Target See all Histone 3 (H3) Antibodies
- Histone 3 (H3)
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Binding Specificity
- meArg2
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This Histone 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by Protein A.
- Immunogen
- Recombinant protein
- Clone
- 2C3
- Isotype
- IgG
- Top Product
- Discover our top product H3 Primary Antibody
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- Application Notes
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WB 1:300-5000
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- Histone 3 (H3)
- Alternative Name
- Histone H3 (H3 Products)
- Synonyms
- H-3 antibody, histocompatibility 3 antibody, H3 antibody
- Background
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Synonyms: HIST1 cluster, H3J antibody, Histone gene cluster 1, H3 histone family, member E antibody, Histone gene cluster 1, H3G antibody, H3 histone family, member J antibody, HIST1 cluster, H3E antibody, HIST1 cluster, H3I antibody, Histone gene cluster 1, H3C antibody, FLJ92264 antibody, H3 histone family, member A antibody
Background: Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
- Gene ID
- 8290
- UniProt
- P68431
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