NLRC5 antibody (N-Term)

Catalog No. ABIN6991398

Product Details anti-NLRC5 Antibody

Target: NLRC5 (NLR Family, CARD Domain Containing 5 (NLRC5))

Binding Specificity: AA 20-70, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRC5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: NOD4 antibody is predicted to not cross-react with other members of the NOD family of proteins.

Purification: NOD4 Antibody is affinity chromatography purified via peptide column.

Immunogen: NOD4 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NOD4. The immunogen is located within amino acids 20 - 70 of NOD4.

Isotype: IgG

Application Details

Application Notes: NOD4 antibody can be used for detection of NOD4 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: NOD4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: NOD4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NLRC5

Target: NLRC5 (NLR Family, CARD Domain Containing 5 (NLRC5))

Alternative Name: NOD4 (NLRC5 Products)

Synonyms: NOD4 antibody, CLR16.1 antibody, NOD27 antibody, AI451557 antibody, AK220210 antibody, NLR family CARD domain containing 5 antibody, NLR family, CARD domain containing 5 antibody, NLRC5 antibody, nlrc5 antibody, Nlrc5 antibody

Background: NOD4 Antibody: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-κ,B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

Molecular Weight: 205 kDa

Gene ID: 84166

NCBI Accession: NP_115582

UniProt: Q86WI3