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GAD65 antibody
GAD2
Reactivity: Human
IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GAD65 Antibody
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Target
See all GAD65 (GAD2) Antibodies
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Reactivity
All reactivities for GAD65 antibodies
Human
Host
All hosts for GAD65 antibodies
Rabbit
Clonality
All clonalities for GAD65 antibodies
Polyclonal
Conjugate
All conjugates for GAD65 antibodies
This GAD65 antibody is un-conjugated
Application
All applications for GAD65 antibodies
Immunohistochemistry (IHC), ELISA
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Synthetic peptide of human GAD2
Isotype
IgG
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Discover our top product GAD2 Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:25-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.3 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for GAD65
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Target
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Alternative Name
GAD2 (GAD2 Products )
Synonyms
GAD65 antibody, gad65 antibody, F12P19.12 antibody, F12P19_12 antibody, GLUTAMATE DECARBOXYLASE 2 antibody, glutamate decarboxylase 2 antibody, zgc:112198 antibody, 6330404F12Rik antibody, GAD(65) antibody, Gad-2 antibody, glutamate decarboxylase 2 antibody, glutamate decarboxylase 1 antibody, glutamic acid decarboxylase 2 antibody, GAD2 antibody, PTRG_06148 antibody, LOC9324534 antibody, Gad2 antibody, GAD1 antibody, gad2 antibody
Background
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
NCBI Accession
NP_000809
UniProt
Q05329
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