ROR2 antibody

Catalog No. ABIN7010731

Product Details anti-ROR2 Antibody

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROR2 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human ROR2 (NP_004551.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ROR2

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Alternative Name: ROR2 (ROR2 Products)

Synonyms: BDB antibody, BDB1 antibody, NTRKR2 antibody, Ntrkr2 antibody, mRor2 antibody, ROR2 antibody, bdb antibody, bdb1 antibody, Xror2 antibody, ntrkr2 antibody, MGC97773 antibody, LOC100219935 antibody, ror2 antibody, xror2 antibody, receptor tyrosine kinase like orphan receptor 2 antibody, receptor tyrosine kinase-like orphan receptor 2 antibody, receptor tyrosine kinase like orphan receptor 2 L homeolog antibody, ROR2 antibody, Ror2 antibody, ror2 antibody, ror2.L antibody

Background: The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.

Molecular Weight:

Observed_MW: 135 kDa

Calculated_MW: 104 kDa

Gene ID: 4920

UniProt: Q01974

Pathways: RTK Signaling, WNT Signaling