IRS1 antibody (pSer307)
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- Target See all IRS1 Antibodies
- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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Binding Specificity
- pSer307
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRS1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogen
- A synthetic phosphorylated peptide around S307 of human IRS1 (NP_005535.1).
- Isotype
- IgG
- Top Product
- Discover our top product IRS1 Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IRS1 (Insulin Receptor Substrate 1 (IRS1))
- Alternative Name
- IRS1 (IRS1 Products)
- Synonyms
- HIRS-1 antibody, G972R antibody, IRS-1 antibody, IRS1IRM antibody, irs1 antibody, irsu antibody, IRS1 antibody, irs-1 antibody, irs1-a antibody, insulin receptor substrate 1 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 1 S homeolog antibody, IRS1 antibody, Irs1 antibody, irs2 antibody, irs1.S antibody
- Background
- This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.
- Molecular Weight
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Observed_MW: 200 kDa
Calculated_MW: 131 kDa
- Gene ID
- 3667
- UniProt
- P35568
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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