LAT2 antibody

Catalog No. ABIN7074503

Product Details anti-LAT2 Antibody

Target: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAT2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse LAT2

Application Details

Application Notes: IHC/IF (M,R) 1:300-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for LAT2

Target: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Alternative Name: LAT2 (LAT2 Products)

Synonyms: LAB antibody, NTAL antibody, WBSCR15 antibody, WBSCR5 antibody, WSCR5 antibody, LAT2 antibody, MGC139435 antibody, Ntal antibody, Wbscr5 antibody, AW125574 antibody, Wbscr15 antibody, linker for activation of T-cells family member 2 antibody, linker for activation of T cells family, member 2 antibody, LAT2 antibody, Lat2 antibody

Background: L-amino acid transporter protein-2 (LAT2), a non-glycosylated membrane protein, complexes with CD98 to contribute to readsorption of neutral amino acids in renal epithelia and blood-tissue barriers. The gene encoding LAT2 is expressed primarily in the kidney, but also to a lesser extent in placenta, brain, liver, spleen, skeletal muscle, heart, small intestine, and lung. Transfection with the antisense sequence of LAT2 suggests that LAT2 expression plays a major role in net basolateral efflux of cysteine, and points to LAT2 as a candidate gene to modulate cysteine reabsorption.

Gene ID: 50934

UniProt: Q9QXW9

Pathways: Fc-epsilon Receptor Signaling Pathway, BCR Signaling