NOTCH4 antibody
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- Target See all NOTCH4 Antibodies
- NOTCH4 (Notch 4 (NOTCH4))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NOTCH4 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse NOTCH4
- Top Product
- Discover our top product NOTCH4 Primary Antibody
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anti-Notch 4 (NOTCH4) (AA 1715-2001) antibody
NOTCH4 Reactivity: Human WB, ELISA, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (Middle Region) antibodyNOTCH4 Reactivity: Human, Rat, Cow, Horse, Guinea Pig, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Notch 4 (NOTCH4) antibodyNOTCH4 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 371-420) antibodyNOTCH4 Reactivity: Human, Cow, Horse, Guinea Pig, Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1261-1273) antibodyVerified NOTCH4 Reactivity: Human, Mouse ELISA, IF Host: Goat Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1824-2003) antibodyNOTCH4 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (Middle Region) antibodyNOTCH4 Reactivity: Human, Cow, Horse, Guinea Pig, Pig, Dog, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (Cleaved-Val1432) antibodyNOTCH4 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (cleaved), (Val1432) antibodyNOTCH4 Reactivity: Human, Monkey WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1819-1851), (C-Term) antibodyNOTCH4 Reactivity: Human WB Host: Rabbit Polyclonal RB52895 unconjugated
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- Application Notes
- IHC/IF (H) 1:600-1:1200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- NOTCH4 (Notch 4 (NOTCH4))
- Alternative Name
- Notch4 (NOTCH4 Products)
- Synonyms
- INT3 antibody, NOTCH3 antibody, Int-3 antibody, Int3 antibody, N4 antibody, Notch4 antibody, notch 4 antibody, neurogenic locus notch homolog protein 4 antibody, NOTCH4 antibody, Notch4 antibody, LOC100712850 antibody
- Background
- Notch4 is a member of the Notch family. The Notch4 signaling network is an evolutionarily conserved intracellular pathway that regulates physical cell to cell interactions. The Notch4 protein, once cleaved from the trans-Golgi network, is presented on the cell surface as a heterodimer. Notch4 regulates cell-fate determination as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1. In Drosophila, once these ligands are activated via the release of the notch intracellular domain (NICD), Notch4 forms a transcriptional activator complex with RBPJ/RBPSUH which then activates the genes of the Enhancer of Split (E(spl)) locus. Notch4 also plays a role in vascular, renal and hepatic development, the implementation of differentiation, proliferation and apoptotic programs, and the regulation of branching morphogenesis in the development of the vascular system.
- Gene ID
- 18132
- NCBI Accession
- NP_035059
- UniProt
- P31695
- Pathways
- Notch Signaling
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