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CD11b antibody (APC-Cy7)

GMP Grade ITGAM Reactivity: Human FACS Host: Mouse Monoclonal OKM1 APC-Cy7
Catalog No. ABIN7076332
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 249
    • 156
    • 61
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 132
    • 99
    • 95
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 234
    • 93
    • 1
    Monoclonal
    Conjugate
    • 108
    • 37
    • 29
    • 25
    • 19
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is conjugated to APC-Cy7
    Application
    • 248
    • 78
    • 74
    • 69
    • 55
    • 36
    • 36
    • 23
    • 20
    • 18
    • 13
    • 13
    • 7
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    • 5
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    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Purity
    >95 %
    Grade
    GMP Grade
    Immunogen
    Human PBMC
    Clone
    OKM1
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Application Notes
    FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.2, 0.09 % sodium azide and 0.2 % (w/v) BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    CD11b (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    The clone OKM1, a mouse monoclonal antibody, binds with a 165 kDa adhesion glycoprotein present in human cells known as CD11b that associates with the 95 kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3)
    Gene ID
    3684
    NCBI Accession
    NM_000632
    UniProt
    P11215
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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