CD45 antibody (iFluor™488)
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- Target See all CD45 (PTPRC) Antibodies
- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD45 antibody is conjugated to iFluor™488
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Application
- Flow Cytometry (FACS)
- Characteristics
- The clone 2D1, a mouse monoclonal antibody, recognizes a hematopoietic cell surface glycoprotein antigen with a molecular weight of 180-220 kDa known as CD45. It is present on all human leukocytes including lymphocytes, monocytes, granulocytes, eosinophils, and basophils in peripheral blood. CD45 has a role in signal transduction, modifying signals from other surface molecules. 2D1 has been reported to react weakly with mature circulating erythrocytes and platelets. The antibody also recognizes the human leukocyte common antigen found on cells from spleen, lymph nodes, bone marrow cells and granulocytes.
- Purification
- Purified
- Purity
- >95 %
- Grade
- GMP Grade
- Immunogen
- Human PBMC
- Clone
- 2D1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product PTPRC Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
- Alternative Name
- CD45 (PTPRC Products)
- Synonyms
- PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody
- Background
- The clone 2D1, a mouse monoclonal antibody, recognizes a hematopoietic cell surface glycoprotein antigen with a molecular weight of 180-220 kDa known as CD45. It is present on all human leukocytes including lymphocytes, monocytes, granulocytes, eosinophils, and basophils in peripheral blood. CD45 has a role in signal transduction, modifying signals from other surface molecules. 2D1 has been reported to react weakly with mature circulating erythrocytes and platelets. The antibody also recognizes the human leukocyte common antigen found on cells from spleen, lymph nodes, bone marrow cells and granulocytes.
- Gene ID
- 5788
- NCBI Accession
- NM_002838
- UniProt
- P08575
- Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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