isk antibody, jlns antibody, mink antibody, jlns2 antibody, xkcne1 antibody, KCNE1 antibody, ISK antibody, JLNS antibody, JLNS2 antibody, LQT2/5 antibody, LQT5 antibody, MinK antibody, Isk antibody, m antibody, minK antibody, IsK antibody, nmf190 antibody, potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog antibody, potassium voltage-gated channel, Isk-related family, member 1 antibody, potassium voltage-gated channel subfamily E member 1 antibody, potassium voltage-gated channel subfamily E regulatory subunit 1 antibody, potassium voltage-gated channel, Isk-related subfamily, member 1 antibody, kcne1.L antibody, KCNE1 antibody, LOC474097 antibody, Kcne1 antibody
Background
Synonyms: Background:Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1(PubMed:19219384). Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium(IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart(IKr).