GRK2 antibody (C-Term)
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- Target See all GRK2 (ADRBK1) Antibodies
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GRK2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Dog, Human, Mouse, Pig, Rat
- Purification
- Affinity purified
- Immunogen
- Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.
- Isotype
- IgG1, IgG1 kappa
- Top Product
- Discover our top product ADRBK1 Primary Antibody
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- Application Notes
- Recommended dilution:WB:1:500-1:5000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine ( pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 %,glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
- Alternative Name
- ADRBK1 (ADRBK1 Products)
- Synonyms
- Adrbk-1 antibody, Bark-1 antibody, GRK2 antibody, betaARK1 antibody, BARK1 antibody, BETA-ARK1 antibody, GRK-2 antibody, Grk2 antibody, beta-adrenergic receptor kinase 1 antibody, G protein-coupled receptor kinase 2 antibody, Tsp_00497 antibody, grk2 antibody, Grk2 antibody, GRK2 antibody
- Background
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Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.
Aliases: GRK2, BARK1, BETA-ARK1
- UniProt
- P25098
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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