ROS1 antibody (AA 1-320) (Biotin)
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- Target See all ROS1 Antibodies
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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Binding Specificity
- AA 1-320
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Reactivity
- Arabidopsis thaliana
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ROS1 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Arabidopsis thaliana
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)
- Isotype
- IgG
- Top Product
- Discover our top product ROS1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
- Alternative Name
- ROS1 (ROS1 Products)
- Synonyms
- MCF3 antibody, ROS antibody, c-ros-1 antibody, ROS1C antibody, Ros-1 antibody, c-ros antibody, ROS proto-oncogene 1, receptor tyrosine kinase antibody, ROS proto-oncogene 1 , receptor tyrosine kinase antibody, Ros1 proto-oncogene antibody, ROS1 antibody, Ros1 antibody
- Background
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Background: Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed:25240767). Generates 3\'-phosphor-alpha,beta-unsaturated aldehyde (3\'-PUA) as a primary 5-meC excision intermediate (PubMed:25228464). Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair (PubMed:24155752).
Aliases: ROS1 antibody, DML1 antibody, At2g36490 antibody, F1O11.12 antibody, DNA glycosylase/AP lyase ROS1 antibody, EC 4.2.99.18 antibody, DEMETER-like protein 1 antibody, Protein REPRESSOR OF SILENCING 1 antibody, Protein ROS1 antibody
- UniProt
- Q9SJQ6
- Pathways
- RTK Signaling
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