KCNJ1 antibody (AA 165-379)

Catalog No. ABIN7145017

Product Details anti-KCNJ1 Antibody

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Binding Specificity: AA 165-379

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human ATP-sensitive inward rectifier potassium channel 10 protein (165-379AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KCNJ1

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Alternative Name: KCNJ1 (KCNJ1 Products)

Synonyms: KIR1.1 antibody, ROMK antibody, ROMK1 antibody, kir1.1 antibody, romk1 antibody, Kcnj antibody, Kir1.1 antibody, Romk2 antibody, kcnj1 antibody, wu:fl37c05 antibody, zgc:63534 antibody, potassium voltage-gated channel subfamily J member 1 antibody, potassium voltage-gated channel subfamily J member 1 L homeolog antibody, potassium inwardly-rectifying channel, subfamily J, member 1 antibody, potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 antibody, KCNJ1 antibody, kcnj1.L antibody, kcnj1 antibody, Kcnj1 antibody, kcnj1a.1 antibody

Background:

Background: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.

Aliases: inwardly rectifying subfamily J member 10 antibody, ATP dependent inwardly rectifying potassium channel Kir4.1 antibody, ATP sensitive inward rectifier potassium channel 10 antibody, ATP-dependent inwardly rectifying potassium channel Kir4.1 antibody, ATP-sensitive inward rectifier potassium channel 10 antibody, BIRK10 antibody, Glial ATP dependent inwardly rectifying potassium channel KIR4.1 antibody, Inward rectifier K(+) channel Kir1.2 antibody, Inward rectifier K+ channel KIR1.2 antibody, Inwardly rectifying potassium channel Kir1.2 antibody, KCJ10_HUMAN antibody, KCNJ 10 antibody, Kcnj10 antibody, KCNJ13 PEN antibody, KIR1.2 antibody, KIR4.1 antibody, Potassium channel antibody, Potassium channel inwardly rectifying subfamily J member 10 antibody, Potassium inwardly rectifying channel subfamily J member 10 antibody, SESAME antibody

UniProt: P78508