GAB1 antibody (AA 119-329)

Catalog No. ABIN7372688

Product Details anti-GAB1 Antibody

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Binding Specificity: AA 119-329

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human GRB2-associated-binding protein 1 protein (119-329AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GAB1

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Alternative Name: GAB1 (GAB1 Products)

Synonyms: AA408973 antibody, AW107238 antibody, growth factor receptor bound protein 2-associated protein 1 antibody, GRB2-associated binding protein 1 antibody, GRB2 associated binding protein 1 antibody, Gab1 antibody, GAB1 antibody

Background:

Background: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).

Aliases: Gab 1 antibody, GAB1 antibody, GAB1_HUMAN antibody, GRB 2 associated binder 1 antibody, GRB 2 associated binding protein 1 antibody, GRB2 associated binding protein 1 isoform a antibody, GRB2 associated binding protein 1 isoform b antibody, GRB2-associated binder 1 antibody, GRB2-associated-binding protein 1 antibody, Growth factor receptor bound protein 2-associated protein 1 antibody

UniProt: Q13480

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals