GAB1 antibody (AA 1-150)

Catalog No. ABIN7531584

Product Details anti-GAB1 Antibody

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Binding Specificity: AA 1-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: GAB1 Rabbit pAb

Sequence: MSGGEVVCSG WLRKSPPEKK LKRYAWKRRW FVLRSGRLTG DPDVLEYYKN DHAKKPIRII DLNLCQQVDA GLTFNKKEFE NSYIFDINTI DRIFYLVADS EEEMNKWVRC ICDICGFNPT EEDPVKPPGS SLQAPADLPL AINTAPPSTQ

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human GAB1 (NP_997006.1).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GAB1

Target: GAB1 (GRB2-Associated Binding Protein 1 (GAB1))

Alternative Name: GAB1 (GAB1 Products)

Synonyms: AA408973 antibody, AW107238 antibody, growth factor receptor bound protein 2-associated protein 1 antibody, GRB2-associated binding protein 1 antibody, GRB2 associated binding protein 1 antibody, Gab1 antibody, GAB1 antibody

Background: The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.,GAB1,GRB2,Cancer,Signal Transduction,Kinase,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,GAB1

Molecular Weight: 76kDa/80kDa

Gene ID: 2549

UniProt: Q13480

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals