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TXNIP antibody (AA 299-381) (Biotin)

TXNIP Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7172028
  • Target See all TXNIP Antibodies
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Binding Specificity
    • 16
    • 14
    • 9
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 299-381
    Reactivity
    • 67
    • 48
    • 33
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 76
    • 5
    Rabbit
    Clonality
    • 68
    • 13
    Polyclonal
    Conjugate
    • 31
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNIP antibody is conjugated to Biotin
    Application
    • 58
    • 31
    • 15
    • 14
    • 14
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Thioredoxin-interacting protein (299-381AA)
    Isotype
    IgG
    Top Product
    Discover our top product TXNIP Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Alternative Name
    TXNIP (TXNIP Products)
    Synonyms
    EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody
    Background

    Background: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

    Aliases: EST01027 antibody, HHCPA78 antibody, THIF antibody, Thioredoxin binding protein 2 antibody, Thioredoxin interacting protein antibody, Thioredoxin-binding protein 2 antibody, Thioredoxin-interacting protein antibody, TXNIP antibody, TXNIP_HUMAN antibody, Upregulated by 1,25 dihydroxyvitamin D 3 antibody, VDUP1 antibody, Vitamin D3 up-regulated protein 1 antibody

    UniProt
    Q9H3M7
    Pathways
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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