CD11b antibody (FITC)
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- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD11b antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), ELISA
- Cross-Reactivity
- Human
- Purification
- Affinity purified
- Immunogen
- Recombinant Protein
- Isotype
- IgG1, IgG1 kappa
- Top Product
- Discover our top product ITGAM Primary Antibody
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- Application Notes
- Recommended dilution:IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- ITGAM (ITGAM Products)
- Synonyms
- CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
- Background
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Background: 4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate.1. Ling NR et al., eds. (1987) Leucocyte Typing III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-3342. Petty HR nd Todd RF. (1996) Immunol. Today 17:2093. Springer TA (1994) Cell 76:3014. Stewart M et al (1995) Curr Opin Cell Biol 7:690
Aliases: N/A
- UniProt
- P11215
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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