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CD11b antibody (PE)

ITGAM Reactivity: Human FACS, IF, ELISA Host: Mouse Monoclonal PE
Catalog No. ABIN7178496
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 247
    • 155
    • 62
    • 33
    • 17
    • 17
    • 16
    • 14
    • 11
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 132
    • 99
    • 94
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 233
    • 92
    • 1
    Monoclonal
    Conjugate
    • 107
    • 36
    • 29
    • 24
    • 20
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
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    • 4
    • 4
    • 3
    • 3
    • 3
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    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is conjugated to PE
    Application
    • 247
    • 78
    • 74
    • 70
    • 54
    • 36
    • 35
    • 22
    • 20
    • 18
    • 13
    • 13
    • 7
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    Flow Cytometry (FACS), Immunofluorescence (IF), ELISA
    Cross-Reactivity
    Human
    Purification
    Affinity purified
    Immunogen
    Recombinant Protein
    Isotype
    IgG1, IgG1 kappa
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    Discover our top product ITGAM Primary Antibody
  • Application Notes
    Recommended dilution:IF:1:100-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered solution, pH 7.4, containing 0.09 % sodium azide and 0.2 % (w/v) BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    ITGAM (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background

    Background: 4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate.1. Ling NR  et al., eds. (1987) Leucocyte Typing  III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-3342. Petty HR nd Todd RF. (1996) Immunol. Today 17:2093. Springer TA (1994) Cell 76:3014. Stewart M et al (1995) Curr Opin Cell Biol 7:690

    Aliases: N/A

    UniProt
    P11215
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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