LRRK2 antibody (AA 2355-2527)

Catalog No. ABIN7531848

Product Details anti-LRRK2 Antibody

Target: LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))

Binding Specificity: AA 2355-2527

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: LRRK2 Rabbit pAb

Sequence: ITVVVDTALY IAKQNSPVVE VWDKKTEKLC GLIDCVHFLR EVMVKENKES KHKMSYSGRV KTLCLQKNTA LWIGTGGGHI LLLDLSTRRL IRVIYNFCNS VRVMMTAQLG SLKNVMLVLG YNRKNTEGTQ KQKEIQSCLT VWDINLPHEV QNLEKHIEVR KELAEKMRRT SVE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2355-2527 of human LRRK2 (NP_940980.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LRRK2

Target: LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))

Alternative Name: LRRK2 (LRRK2 Products)

Synonyms: LRRK2 antibody, AURA17 antibody, DARDARIN antibody, PARK8 antibody, RIPK7 antibody, ROCO2 antibody, 4921513O20Rik antibody, 9330188B09Rik antibody, AW561911 antibody, D630001M17Rik antibody, Gm927 antibody, cI-46 antibody, leucine-rich repeat kinase 2 antibody, leucine rich repeat kinase 2 antibody, lrrk2 antibody, LRRK2 antibody, Lrrk2 antibody

Background: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.,LRRK2,AURA17,DARDARIN,PARK8,RIPK7,ROCO2,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Autophagy,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,LRRK2

Molecular Weight: 286kDa

Gene ID: 120892

UniProt: Q5S007

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development