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ERK1 antibody (pThr185, pThr202, pThr204, pTyr187)
MAPK3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ERK1 Antibody
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Target
See all ERK1 (MAPK3) Antibodies
ERK1 (MAPK3)
(Mitogen-Activated Protein Kinase 3 (MAPK3))
Binding Specificity
All epitopes for ERK1 antibodies
pThr185, pThr202, pThr204, pTyr187
Reactivity
All reactivities for ERK1 antibodies
Human
Host
All hosts for ERK1 antibodies
Rabbit
Clonality
All clonalities for ERK1 antibodies
Polyclonal
Conjugate
All conjugates for ERK1 antibodies
This ERK1 antibody is un-conjugated
Application
All applications for ERK1 antibodies
Western Blotting (WB)
Purpose
Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Rabbit pAb
Cross-Reactivity
Human, Mouse
Characteristics
Phosphorylated Antibodies
Purification
Affinity purification
Immunogen
A phospho specific peptide corresponding to residues surrounding T202/Y204+T185/Y187 of human ERK1+ERK2.
Isotype
IgG
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Discover our top product MAPK3 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for ERK1
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Target
ERK1 (MAPK3)
(Mitogen-Activated Protein Kinase 3 (MAPK3))
Alternative Name
MAPK1/MAPK3 (MAPK3 Products )
Synonyms
ERK-1 antibody, ERK1 antibody, ERT2 antibody, HS44KDAP antibody, HUMKER1A antibody, P44ERK1 antibody, P44MAPK antibody, PRKM3 antibody, p44-ERK1 antibody, p44-MAPK antibody, Erk-1 antibody, Erk1 antibody, Ert2 antibody, Esrk1 antibody, Mnk1 antibody, Mtap2k antibody, Prkm3 antibody, p44 antibody, p44erk1 antibody, p44mapk antibody, ERK3 antibody, ERK6 antibody, P38GAMMA antibody, PRKM12 antibody, SAPK-3 antibody, SAPK3 antibody, fi06b09 antibody, wu:fi06b09 antibody, zERK1 antibody, Tb08.10J17.940 antibody, MAPK1 antibody, MNK1 antibody, AW123708 antibody, Erk6 antibody, P38gamma antibody, Prkm12 antibody, Sapk3 antibody, ATMAPK3 antibody, ATMPK3 antibody, T6D9.4 antibody, mitogen-activated protein kinase 3 antibody, mitogen-activated protein kinase 3 antibody, mitogen-activated protein kinase 12 antibody, mitogen activated protein kinase 3 antibody, mitogen-activated serine/threonine-protein kinase antibody, MAPK3 antibody, Mapk3 antibody, MAPK12 antibody, mapk3 antibody, Tc00.1047053509475.10 antibody, Tb927.8.3550 antibody, Mapk12 antibody, CEK1 antibody, MPK3 antibody
Background
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014],MAPK1/MAPK3
Gene ID
5594, 5595
UniProt
P28482 , P27361
Pathways
MAPK Signaling , RTK Signaling , Interferon-gamma Pathway , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Response to Growth Hormone Stimulus , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Protein targeting to Nucleus , Toll-Like Receptors Cascades , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , VEGFR1 Specific Signals , S100 Proteins
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