SLC3A2 antibody (AA 231-280) (Biotin)
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- Target See all SLC3A2 Antibodies
- SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
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Binding Specificity
- AA 231-280
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Reactivity
- Human, Rat, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC3A2 antibody is conjugated to Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Pig, Rat
- Predicted Reactivity
- Mouse,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CD98
- Isotype
- IgG
- Top Product
- Discover our top product SLC3A2 Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
- Alternative Name
- CD98 (SLC3A2 Products)
- Synonyms
- 4F2 antibody, 4F2HC antibody, 4T2HC antibody, CD98 antibody, CD98HC antibody, MDU1 antibody, NACAE antibody, Mdu1 antibody, MGC53951 antibody, slc3a2 antibody, MGC53965 antibody, SLC3A2 antibody, AI314110 antibody, Cd98 antibody, Ly-10 antibody, Ly-m10 antibody, Ly10 antibody, Mgp-2hc antibody, fc65h12 antibody, wu:fc65h12 antibody, id:ibd1327 antibody, sb:cb519 antibody, wu:fe14a07 antibody, wu:fq18d12 antibody, zgc:55813 antibody, solute carrier family 3 member 2 antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog antibody, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2a antibody, solute carrier family 3 (amino acid transporter heavy chain), member 2b antibody, SLC3A2 antibody, Slc3a2 antibody, slc3a2.L antibody, slc3a2.S antibody, slc3a2a antibody, slc3a2b antibody
- Background
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Synonyms: 4F2, CD98, MDU1, 4F2HC, 4T2HC, NACAE, CD98HC, 4F2 cell-surface antigen heavy chain, 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2, SLC3A2
Background: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
- Gene ID
- 6520
- UniProt
- P08195
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