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Collagen IV antibody (AA 1401-1500)

COL4 Reactivity: Human, Mouse, Rat, Rabbit ELISA, WB, IHC (fro), IHC (p), FACS, IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN728413
  • Target See all Collagen IV (COL4) Antibodies
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    Binding Specificity
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1401-1500
    Reactivity
    • 90
    • 42
    • 40
    • 23
    • 15
    • 11
    • 5
    • 2
    Human, Mouse, Rat, Rabbit
    Host
    • 59
    • 27
    • 13
    Rabbit
    Clonality
    • 71
    • 28
    Polyclonal
    Conjugate
    • 49
    • 10
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Collagen IV antibody is un-conjugated
    Application
    • 61
    • 49
    • 30
    • 28
    • 27
    • 26
    • 25
    • 25
    • 20
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Specificity
    This antibody has 79 % cross reactivity with Collagen alpha-5(IV) chain.
    Cross-Reactivity
    Human, Mouse, Rabbit, Rat
    Predicted Reactivity
    Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Collagen alpha-1(IV) chain
    Isotype
    IgG
    Top Product
    Discover our top product COL4 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    Alternative Name
    Collagen 4 (COL4 Products)
    Synonyms
    collagen, type IV antibody, Let-2 antibody
    Background

    Synonyms: Bru, Raw, Svc, Col4a-1, Del(8)44H, Collagen alpha-1(IV) chain, Col4a1

    Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).

    Gene ID
    12826
    UniProt
    P02463
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