Caspase 9 antibody (AA 301-305)
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- Target See all Caspase 9 (CASP9) Antibodies
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Binding Specificity
- AA 301-305
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 9 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- The antibody detects endogenous level of total Caspase 9 protein.
- Purification
- Affinity purified
- Immunogen
- Peptide sequence around AA 301-305 (T-S-P-E-D) derived from Caspase 9 Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product CASP9 Primary Antibody
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- Application Notes
- Western blotting: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- Alternative Name
- Caspase 9 (CASP9 Products)
- Synonyms
- CASP9 antibody, AI115399 antibody, APAF-3 antibody, AW493809 antibody, CASP-9 antibody, Caspase-9 antibody, ICE-LAP6 antibody, Mch6 antibody, Apaf3 antibody, Casp-9-CTD antibody, Casp9_v1 antibody, Ice-Lap6 antibody, APAF3 antibody, MCH6 antibody, PPP1R56 antibody, caspase 9 antibody, CASP9 antibody, Casp9 antibody
- Background
- Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
- Molecular Weight
- 35 kDa
- Gene ID
- 842
- NCBI Accession
- NP_001220
- UniProt
- P55211
- Pathways
- MAPK Signaling, RTK Signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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