GZMB antibody (AA 21-130) (Alexa Fluor 488)
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- Target See all GZMB Antibodies
- GZMB (Granzyme B (GZMB))
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Binding Specificity
- AA 21-130
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GZMB antibody is conjugated to Alexa Fluor 488
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Specificity
- Specific towards Granzyme B and Granzyme H
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GZMB
- Isotype
- IgG
- Top Product
- Discover our top product GZMB Primary Antibody
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anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB Reactivity: Human, Mouse WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibodyGZMB Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19353 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reactivity: Human IHC, StM Host: Mouse Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reactivity: Human WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 4E4 unconjugated
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- Granzyme B (GZMB Products)
- Synonyms
- CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
- Background
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Synonyms: HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, T-cell serine protease 1-3E, GZMB, GRB, Granzyme B, Granzyme H
Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
- Gene ID
- 3002
- UniProt
- P10144
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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