AXL antibody (AA 466-530)

Catalog No. ABIN931385

Product Details anti-AXL Antibody

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Binding Specificity: AA 466-530

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AXL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: AXL antibody was raised in Mouse using a purified recombinant fragment of AXL(aa466-530) expressed in E. coli as the immunogen.

Clone: 1B3A2

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: AXL (AXL Products)

Synonyms: JTK11 antibody, UFO antibody, AI323647 antibody, Ark antibody, Tyro7 antibody, Ufo antibody, AXL receptor tyrosine kinase antibody, Axl receptor tyrosine kinase antibody, AXL antibody, Axl antibody

Background: AXL is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. Synonyms: Monoclonal AXL antibody, Anti-AXL antibody.

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin