×
For best experience we recommend to activate Javascript in your browser.
NCOA1 antibody (Middle Region)
NCOA1
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NCOA1 Antibody
(hide)
Target
See all NCOA1 Antibodies
NCOA1
(Nuclear Receptor Coactivator 1 (NCOA1))
Binding Specificity
All epitopes for NCOA1 antibodies
AA 593-625, Middle Region
Reactivity
All reactivities for NCOA1 antibodies
Human
Host
All hosts for NCOA1 antibodies
Rabbit
Clonality
All clonalities for NCOA1 antibodies
Polyclonal
Conjugate
All conjugates for NCOA1 antibodies
This NCOA1 antibody is un-conjugated
Application
All applications for NCOA1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes NCOA1/SRC1.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the central region (between 593-625aa) of human NCOA1 / SRC1.
Isotype
Ig Fraction
Top Product
Discover our top product NCOA1 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for NCOA1
(hide)
Target
NCOA1
(Nuclear Receptor Coactivator 1 (NCOA1))
Alternative Name
NCOA1 (NCOA1 Products )
Synonyms
F-SRC-1 antibody, KAT13A antibody, RIP160 antibody, SRC1 antibody, bHLHe42 antibody, bHLHe74 antibody, si:dkey-5g7.6 antibody, si:dkey-34f16.6 antibody, NCOA1 antibody, SRC-1 antibody, nuclear receptor coactivator 1 antibody, NCOA1 antibody, ncoa1 antibody, Ncoa1 antibody
Background
The protein encoded by the NCOA1 gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: BHLHE74, Class E basic helix-loop-helix protein 74, NCoA-1, NY-REN-52, Nuclear receptor coactivator 1, Protein Hin-2, RIP160, SRC-1, Steroid receptor coactivator 1
Gene ID
8648
NCBI Accession
NP_003734
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Nuclear Hormone Receptor Binding , Chromatin Binding , Regulation of Lipid Metabolism by PPARalpha
Recently viewed
(hide)