anti-Mouse (Murine) SQSTM1 antibody for Enzyme Immunoassay

Recommended SQSTM1 Antibody (supplied by: Log in to see )

Antigen
Sequestosome 1 (SQSTM1) Antibodies
  • SQSTM1
  • sqstm1
  • MGC79491
  • A170
  • OSIL
  • PDB3
  • ZIP3
  • p60
  • p62
  • p62B
  • OSF-6
  • Osi
  • STAP
  • ZIP
  • sb:cb621
  • zgc:85784
  • sequestosome 1
  • sequestosome 1 L homeolog
  • SQSTM1
  • sqstm1
  • Sqstm1
  • sqstm1.L
Epitope
C-Term
67
42
36
36
25
20
19
16
15
14
12
12
11
9
9
8
8
6
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
373
190
135
8
5
5
5
5
4
4
2
2
2
2
2
1
1
1
1
Host
Rabbit
314
51
6
3
Clonality
Polyclonal
Conjugate
This SQSTM1 antibody is un-conjugated
19
17
16
12
12
12
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
310
122
102
97
73
70
38
36
28
22
18
13
4
2
2
Supplier
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Catalog No. ABIN615711
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5553898 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0

General

Antigen Sequestosome 1 (SQSTM1) Antibodies
Epitope C-Term
(67), (42), (36), (36), (25), (20), (19), (16), (15), (14), (12), (12), (11), (9), (9), (8), (8), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(373), (190), (135), (8), (5), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(314), (51), (6), (3)
Clonality
Polyclonal
Conjugate This SQSTM1 antibody is un-conjugated
(19), (17), (16), (12), (12), (12), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(310), (122), (102), (97), (73), (70), (38), (36), (28), (22), (18), (13), (4), (2), (2)
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Product Details anti-SQSTM1 Antibody

Target Details SQSTM1 Application Details Handling Images
Specificity Recognizes SQSTM1 (C-term).
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen A 14 amino acid peptide from near the carboxy terminus of Human SQSTM1. Genename: SQSTM1
Plasmids, Primers & others

Target Details SQSTM1

Product Details anti-SQSTM1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SQSTM1 (SQSTM1 Antibody Abstract)
Background SQSTM1/p62 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NF-kappaB by TNF-alpha, nerve growth factor (NGF) and interleukin-1. SQSTM1/p62, a co-interacting protein of the atypical PKC isoforms, has a UBA domain at its C-terminal end, which binds non-covalently to polyubiquitin chain. SQSTM1's UBA domain is necessary for recruitment of polyubiquitin and aggresome formation. SQSTM1 may play a role in titin/TTN downstream signaling in muscle cells and may be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels. Mutations in the ubiquitin-associated (UBA) domain of SQSTM1 commonly cause Paget's disease of bone since the UBA is necessary for aggregate sequestration and cell survival.Synonyms: EBI3-associated protein of 60 kDa, EBIAP, ORCA, OSIL, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Sequestosome-1, Ubiquitin-binding protein p62, p60, p62
Gene ID 8878
NCBI Accession NP_001135770
UniProt Q13501
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy

Application Details

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-SQSTM1 Antibody Target Details SQSTM1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Sequestosome 1 (SQSTM1) (C-Term) antibody (ABIN615711) Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blotting (WB) image for anti-Sequestosome 1 (SQSTM1) (C-Term) antibody (ABIN615711) Western blot analysis of SQSTM1 in Human spleen tissue lysate with SQSTM1 antibody at...