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|Antigen||Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This CDKN1B antibody is un-conjugated Alternatives|
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|Supplier||Log in to see|
Product Details anti-CDKN1B AntibodyTarget Details CDKN1B Application Details Handling Images
This antibody is specific to a protein of 27 kDa known as p27Kip1 a cell cycle regulatory mitotic inhibitor. This antibody recognizes an epitope between amino acids 83-204 of p27. It does not show any cross reactivity with other related mitotic inhibitors.
Cellular Localization: Nuclear.
|Immunogen||BALB/C mice were injected with Mouse recombinant p27 protein.|
|Plasmids, Primers & others|
Target Details CDKN1BProduct Details anti-CDKN1B Antibody Application Details Handling Images back to top
|Alternative Name||CDKN1B / KIP1 (CDKN1B Antibody Abstract)|
|Background||Synonyms: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1|
|Pathways||Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy|
Application DetailsProduct Details anti-CDKN1B Antibody Target Details CDKN1B Handling Images back to top
Immunoprecipitation: 1: 50. Western Blot: 1: 50 to 1: 100. Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 25-1: 50 in an ABC method (30-60 minutes at room temperature)Recommended Positive Control: Colan carcinoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CDKN1B Antibody Target Details CDKN1B Application Details Images back to top
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||This product is photosensitive and should be protected from light|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month. DO NOT FREEZE!|
ImagesProduct Details anti-CDKN1B Antibody Target Details CDKN1B Application Details Handling back to top