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CHN1 Products

(rho GTPase Activating Protein 2 (ARHGAP2))

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This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011].

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Featured CHN1 Categories

CHN1 Antibodies

High quality antibodies with extensive validation data.

CHN1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CHN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CHN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN514400
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (7)
Cat. No. ABIN1499629
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p), FACS
Validations
  • (9)
Cat. No. ABIN1499627
Quantity 100 μL
Datasheet Datasheet

Recommended CHN1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1143991
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1143990
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1143989
Quantity 96 tests
Datasheet Datasheet

Recommended CHN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349368
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349366
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091647
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CHN1 products

Nie, Di Nardo, Han, Baharanyi, Kramvis, Huynh, Dabora, Codeluppi, Pandolfi, Pasquale, Sahin: "Tsc2-Rheb signaling regulates EphA-mediated axon guidance." in: Nature neuroscience, Vol. 13, Issue 2, pp. 163-72, (2010) (PubMed).

Volk, Fricke, Strobl, Kolling, Kubisch, Neugebauer: "Analysis of the CHN1 gene in patients with various types of congenital ocular motility disorders." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 248, Issue 9, pp. 1351-7, (2010) (PubMed).

Murillo-Correa, Kon-Jara, Engle, Zenteno: "Clinical features associated with an I126M alpha2-chimaerin mutation in a family with autosomal-dominant Duane retraction syndrome." in: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus, Vol. 13, Issue 3, pp. 245-8, (2009) (PubMed).

Wang, Yang, Leskow, Sun, Canagarajah, Hurley, Kazanietz: "Phospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signaling." in: The EMBO journal, Vol. 25, Issue 10, pp. 2062-74, (2006) (PubMed).

Ridley: "Cyclin' round the cell with Rac." in: Developmental cell, Vol. 1, Issue 2, pp. 160-1, (2001) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Synonyms and alternative names related to CHN1

chimerin 1 (CHN1), chimerin 1 (Chn1), chimerin 1 L homeolog (chn1.L), chimerin 1 (chn1), 0610007I19Rik, 0710001E19Rik, 1700112L09Rik, 2900046J01Rik, AI413815, ARHGAP2, chimaerin, CHN, DURS2, N-chimaerin, NC, RHOGAP2, wu:fr89a09, zgc:56160, zgc:92906

Protein level used designations for CHN1

  • A-chimaerin
  • N-chimaerin
  • Rho GTPase-activating protein 2
  • a2-chimaerin
  • alpha-chimerin
  • chimaerin 1
  • chimerin (chimaerin) 1
  • n-chimerin
  • N-chimerin
  • NC
  • rho GTPase-activating protein 2
  • alpha1 chimaerin
  • alpha2 chimaerin
  • alpha3-chimerin
  • chimaerin
  • alpha chimerin
  • z-chimaerin
  • N-chimaerin-like
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