anti-Human LARS antibody for Enzyme Immunoassay

Recommended LARS Antibody (supplied by: Log in to see )

Antigen
Leucyl-tRNA Synthetase (LARS) Antibodies
  • HSPC192
  • LARS1
  • LEURS
  • LEUS
  • LRS
  • PIG44
  • RNTLS
  • hr025Cl
  • CG7479
  • Dmel\\CG7479
  • LeuRS
  • F21M12.1
  • F21M12_1
  • BA4991
  • DDBDRAFT_0183834
  • DDBDRAFT_0231251
  • DDB_0183834
  • DDB_0231251
  • 2310045K21Rik
  • 3110009L02Rik
  • AW536573
  • mKIAA1352
  • leucyl-tRNA synthetase
  • Leucyl-tRNA synthetase, mitochondrial
  • ATP binding/leucine-tRNA ligases/aminoacyl-tRNA ligase
  • leucine--tRNA ligase
  • leucyl-tRNA synthetase LeuS
  • leucyl-tRNA ligase
  • leucine-tRNA ligase
  • LARS
  • LeuRS-m
  • AT1G09620
  • leuS
  • APH_RS02290
  • mleuS
  • Lars
Epitope
N-Term, AA 183-213
5
5
3
3
2
1
1
1
Reactivity
Human, Mouse (Murine)
24
14
6
2
1
1
1
1
1
1
Host
Rabbit
27
Clonality
Polyclonal
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
26
13
7
6
5
4
3
3
3
1
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Catalog No. ABIN953139
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
7 ABIN359572 EIA IHC (p) WB Rabbit Ig Fraction C-Term Log in to see Polyclonal 3

General

Antigen Leucyl-tRNA Synthetase (LARS) Antibodies
Epitope N-Term, AA 183-213
(5), (5), (3), (3), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(24), (14), (6), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(27)
Clonality
Polyclonal
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
(26), (13), (7), (6), (5), (4), (3), (3), (3), (1)
Pubmed 4 references available
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Product Details anti-LARS Antibody

Target Details LARS Application Details Handling References for anti-LARS antibody (ABIN953139) Images
Specificity This antibody recognizes Human and Mouse LARS (N-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 183-213 amino acids from the N-terminal region of Human LARS.
Isotype Ig Fraction
Plasmids, Primers & others

Target Details LARS

Product Details anti-LARS Antibody Application Details Handling References for anti-LARS antibody (ABIN953139) Images back to top
Antigen
Alternative Name LARS (LARS Antibody Abstract)
Background This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. Alternatively spliced transcript variants of this gene have been found, however, their full-length nature is not known.Synonyms: EC=6.1.1.4, KIAA1352, LARS, LeuRS, Leucine-tRNA ligase, Leucyl-tRNA synthetase, cytoplasmic
Molecular Weight 134466 Da
Gene ID 51520
NCBI Accession NP_064502
Pathways EGFR Signaling Pathway

Application Details

Product Details anti-LARS Antibody Target Details LARS Handling References for anti-LARS antibody (ABIN953139) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-LARS Antibody Target Details LARS Application Details References for anti-LARS antibody (ABIN953139) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-LARS antibody (ABIN953139)

Product Details anti-LARS Antibody Target Details LARS Application Details Handling Images back to top
Background publications

Pang, Martinis: "A paradigm shift for the amino acid editing mechanism of human cytoplasmic leucyl-tRNA synthetase." in: Biochemistry, Vol. 48, Issue 38, pp. 8958-64, 2009

Seiradake, Mao, Hernandez, Baker, Plattner, Alley, Cusack: "Crystal structures of the human and fungal cytosolic Leucyl-tRNA synthetase editing domains: A structural basis for the rational design of antifungal benzoxaboroles." in: Journal of molecular biology, Vol. 390, Issue 2, pp. 196-207, 2009

Shin, Kim, Jung, Xu, Jeong, Chung: "Implication of leucyl-tRNA synthetase 1 (LARS1) over-expression in growth and migration of lung cancer cells detected by siRNA targeted knock-down analysis." in: Experimental & molecular medicine, Vol. 40, Issue 2, pp. 229-36, 2008

Maeso, Rueda, Jiménez, Del Hoyo, Martín, Cabello, Mendoza, Arenas, Campos: "A novel mutation in the mitochondrial DNA tRNA Leu (UUR) gene associated with late-onset ocular myopathy." in: Neuromuscular disorders : NMD, Vol. 17, Issue 5, pp. 415-8, 2007

Images

Product Details anti-LARS Antibody Target Details LARS Application Details Handling References for anti-LARS antibody (ABIN953139) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Leucyl-tRNA Synthetase (LARS) (AA 183-213), (N-Term) antibody (ABIN953139) Flow cytometric analysis of Hela cells using LARS Antibody (N-term) Cat.-No AP52444PU...
Western Blotting (WB) image for anti-Leucyl-tRNA Synthetase (LARS) (AA 183-213), (N-Term) antibody (ABIN953139) Western blot analysis of LARS Antibody (N-term) in mouse Neuro-2a cell line lysates (...