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|Antigen||Cystathionase (Cystathionine gamma-Lyase) (CTH) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CTH antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|1 reference available|
Product Details anti-CTH AntibodyTarget Details CTH Application Details Handling References for anti-CTH antibody (ABIN1387469) Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human Cystathionine gamma lyase|
|Plasmids, Primers & others|
Target Details CTHProduct Details anti-CTH Antibody Application Details Handling References for anti-CTH antibody (ABIN1387469) Images back to top
|Alternative Name||CTH (CTH Antibody Abstract)|
Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.
Synonyms: CGL_HUMAN, CTH, Cystathionine gamma lyase, Cystathionine gamma-lyase, Cysteine desulfhydrase, Gamma cystathionase, Gamma-cystathionase, Homoserine deaminase, Homoserine dehydratase, MGC9471, CSE, Cystathionase.
Application DetailsProduct Details anti-CTH Antibody Target Details CTH Handling References for anti-CTH antibody (ABIN1387469) Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-CTH Antibody Target Details CTH Application Details References for anti-CTH antibody (ABIN1387469) Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
References for anti-CTH antibody (ABIN1387469)Product Details anti-CTH Antibody Target Details CTH Application Details Handling Images back to top
|Product cited in:||
Shiina, Shima, Horii, Naitou, Nakamori, Sano, Shimizu: "Inhibitory action of hydrogen sulfide on esophageal striated muscle motility in rats." in: European journal of pharmacology, Vol. 771, pp. 123-9, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).
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