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IL-10 Proteins

(Interleukin 10 (IL10))
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].

Active filters:

  • Target: IL-10 (IL10)
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7956246
IL-10 Protein IL10 · Protein Rat Escherichia coli (E. coli)
$1,736.90 View price
  • 100 μg
  • 10 μg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7958819
IL-10 Protein (His tag) IL10 · Protein Human Escherichia coli (E. coli)
$851.40 View price
  • 50 μg
  • 1 mg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7942275
IL-10 Protein (His tag) IL10 · Protein Human Mammalian Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
$705.00 View price
  • 100 μg
  • 1 mg
  • 50 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7956928
IL-10 Protein IL10 · Protein Mouse Escherichia coli (E. coli)
$2,376.00 View price
  • 100 μg
  • 1 mg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7956104
IL-10 Protein IL10 · Protein Mouse Escherichia coli (E. coli)
$1,736.90 View price
  • 100 μg
  • 10 μg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7956926
IL-10 Protein IL10 · Protein Human Escherichia coli (E. coli)
$2,376.00 View price
  • 100 μg
  • 1 mg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7959785
IL-10 Protein IL10 · Protein Mouse Escherichia coli (E. coli)
$851.40 View price
  • 50 μg
  • 1 mg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7960261
IL-10 Protein IL10 · Protein Human Human Cells
$851.40 View price
  • 50 μg
  • 1 mg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN6120117
IL-10 Protein (His tag) IL10 · Protein Rabbit HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
$1,288.86 View price
  • 100 μg
  • 1 mg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN6123882
IL-10 Protein (His tag) IL10 · Protein Guinea Pig Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
$580.46 View price
  • 50 μg
  • 1 mg
  • 100 μg
  • 200 μg
  • 500 μg
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN6120109
IL-10 Protein (AA 20-181) (His tag) IL10 · Protein Dog HEK-293F Cells
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
$1,335.06 View price
  • 100 μg
  • 1 mg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN6380531
IL-10 Protein (His tag,GST tag) IL10 · Protein Chicken Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
$3,290.86 View price
  • 1 mg
  • 50 μg
  • 100 μg
  • 200 μg
  • 500 μg
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN6380527
IL-10 Protein (His tag) IL10 · Protein Goat Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
$2,721.06 View price
  • 1 mg
  • 50 μg
  • 100 μg
  • 200 μg
  • 500 μg
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN6120291
IL-10 Protein (His tag) IL10 · Protein Monkey Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
$857.66 View price
  • 100 μg
  • 1 mg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 10 to 20 Business Days Shipping to: United States
Protein
Origin
Rat
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 97 % by SDS-PAGE and HPLC analyses.
Biological Activity
Active
Catalog No. ABIN7956246
$1,736.90
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7958819
$851.40
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • ELISA (ELISA: Listed application)
Origin
Human
Host
Mammalian Cells
Protein Type
Recombinant
Catalog No. ABIN7942275
$705.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>97 % as determined by SDS-PAGE and HPLC.
Biological Activity
Active
Catalog No. ABIN7956928
$2,376.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 97 % by SDS-PAGE and HPLC analyses.
Biological Activity
Active
Catalog No. ABIN7956104
$1,736.90
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>95 % as determined by SDS-PAGE and HPLC.
Biological Activity
Active
Catalog No. ABIN7956926
$2,376.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7959785
$851.40
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Human
Host
Human Cells
Protein Type
Recombinant
Purity
Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7960261
$851.40
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Rabbit
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN6120117
$1,288.86
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Guinea Pig
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN6123882
$580.46
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Dog
Host
HEK-293F Cells
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN6120109
$1,335.06
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Chicken
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN6380531
$3,290.86
Plus shipping costs $50.00
1 mg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Goat
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN6380527
$2,721.06
Plus shipping costs $50.00
1 mg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Monkey
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN6120291
$857.66
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days

Latest Publications for our IL-10 Proteins

Phadnis-Moghe, Crawford, Kaminski: "Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 144, Issue 1, pp. 39-50, (2015) (PubMed).

Larson, Hübner, Torrero, Morris, Brankin, Swierczewski, Davies, Vonakis, Mitre: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).

Yang, Hirose, Takahashi, Kawakatsu, Takaiwa: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).

Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).

van der Vliet, Wang, Yue, Koon, Balk, Exley: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Schlaak, Schmitt, Hüls, Meyer zum Büschenfelde, Fleischer: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).

Feng, Tang, Chang, Wilson: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).

Howard, OGarra, Ishida, de Waal Malefyt, de Vries: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).

Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).

Aliases for IL-10 Proteins

interleukin 10 (IL10) Proteins
interleukin 10 (Il10) Proteins
CSIF Proteins
GVHDS Proteins
IL-10 Proteins
Il-10 Proteins
IL10A Proteins
IL10X Proteins
TGIF Proteins
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