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IL-10 Proteins

(Interleukin 10 (IL10))
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].

Active filters:

  • Target: IL-10 (IL10)
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN5713542
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Macaca (Macaque) Yeast
  • SDS (SDS-PAGE: Validation image available)
$936.10 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 20 μg
  • 200 μg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN2870745
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Mouse HEK-293 Cells
  • SDS (SDS-PAGE: Validation image available)
$520.92 View price
  • 50 μg
  • 1 mg
  • 10 μg
  • 20 μg
Delivery in 2 to 4 Business Days Shipping to: United States
ABIN3010149
IL-10 Protein (His tag) IL10 · Protein Cow Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Validation image available)
  • WB (Western Blotting: Listed application)
$919.26 View price
  • 100 μg
  • 1 mg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 10 to 20 Business Days Shipping to: United States
ABIN2723581
IL-10 Protein (Myc-DYKDDDDK Tag) IL10 · Protein Human HEK-293 Cells
  • WB (Western Blotting: Validation image available)
  • STD (Standard: Listed application)
  • AbP (Antibody Production: Listed application)
$1,112.40 View price
  • 20 μg
Delivery in 16 to 17 Business Days Shipping to: United States
ABIN6239730
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Human HEK-293 Cells
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
$837.00 View price
  • 50 μg
  • 1 mg
Delivery in 15 to 19 Business Days Shipping to: United States
ABIN1677108
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Llama Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1656189
IL-10 Protein (AA 19-164) (His tag) IL10 · Protein Orcinus orca Yeast
  • ELISA (ELISA: Listed application)
$2,479.54 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1653548
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Marmota monax Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1654659
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Chimpanzee Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1638891
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Squirrel Monkey Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1650464
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Rabbit Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1634607
IL-10 Protein (AA 22-175) (His tag) IL10 · Protein Chicken Yeast
  • ELISA (ELISA: Listed application)
$2,507.01 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1621724
IL-10 Protein (AA 20-179) (His tag) IL10 · Protein Fox Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1621235
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Horse Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1635729
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Baboon Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN7479374
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Callithrix jacchus Yeast
  • ELISA (ELISA: Listed application)
$810.17 View price
  • 100 μg
  • 1 mg
  • 20 μg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1622204
IL-10 Protein (AA 19-175) (His tag) IL10 · Protein Pig Yeast
  • ELISA (ELISA: Listed application)
$2,516.82 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN7584808
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Rat Yeast
  • ELISA (ELISA: Listed application)
$1,155.42 View price
  • 100 μg
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1458638
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Cat Yeast
  • ELISA (ELISA: Listed application)
$2,526.62 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN1461283
IL-10 Protein (AA 20-181) (His tag) IL10 · Protein Dog Yeast
  • ELISA (ELISA: Listed application)
$2,534.48 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
Protein
  • SDS (SDS-PAGE: Validation image available)
Origin
Macaca (Macaque)
Host
Yeast
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN5713542
$936.10
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
>92 % as determined by SDS-PAGE.
Catalog No. ABIN2870745
$520.92
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 2 to 4 Business Days
Protein
  • SDS (SDS-PAGE: Validation image available)
  • WB (Western Blotting: Listed application)
Origin
Cow
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN3010149
$919.26
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 20 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • STD (Standard: Listed application)
  • AbP (Antibody Production: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2723581
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Protein
  • AcA (Activity Assay: Listed application)
  • CC (Cell Culture: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 97 %
Biological Activity
Active
Catalog No. ABIN6239730
$837.00
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Llama
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1677108
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Orcinus orca
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1656189
$2,479.54
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Marmota monax
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1653548
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Chimpanzee
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1654659
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Squirrel Monkey
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1638891
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Rabbit
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1650464
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Chicken
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1634607
$2,507.01
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Fox
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1621724
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Horse
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1621235
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Baboon
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1635729
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Callithrix jacchus
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7479374
$810.17
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Pig
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1622204
$2,516.82
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Rat
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7584808
$1,155.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Cat
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1458638
$2,526.62
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Dog
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1461283
$2,534.48
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days

Latest Publications for our IL-10 Proteins

Phadnis-Moghe, Crawford, Kaminski: "Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 144, Issue 1, pp. 39-50, (2015) (PubMed).

Larson, Hübner, Torrero, Morris, Brankin, Swierczewski, Davies, Vonakis, Mitre: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).

Yang, Hirose, Takahashi, Kawakatsu, Takaiwa: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).

Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).

van der Vliet, Wang, Yue, Koon, Balk, Exley: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Schlaak, Schmitt, Hüls, Meyer zum Büschenfelde, Fleischer: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).

Feng, Tang, Chang, Wilson: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).

Howard, OGarra, Ishida, de Waal Malefyt, de Vries: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).

Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).

Aliases for IL-10 Proteins

interleukin 10 (IL10) Proteins
interleukin 10 (Il10) Proteins
CSIF Proteins
GVHDS Proteins
IL-10 Proteins
Il-10 Proteins
IL10A Proteins
IL10X Proteins
TGIF Proteins
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