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IL-10 Proteins

(Interleukin 10 (IL10))
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].

Active filters:

  • Target: IL-10 (IL10)
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7387460
IL-10 Protein (AA 19-175) (His tag,GST tag) IL10 · Protein Pig Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$1,039.24 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7387448
IL-10 Protein (AA 22-175) (His tag,GST tag) IL10 · Protein Chicken Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$879.00 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7414903
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Rhesus Monkey Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$785.85 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7321255
IL-10 Protein (AA 19-178) IL10 · Protein Rat Escherichia coli (E. coli)
$474.65 View price
  • 20 μg
  • 10 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN8056997
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Mouse Escherichia coli (E. coli)
  • Imm (Immunogen: Listed application)
$680.09 View price
  • 100 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN8056998
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Mouse HEK-293 Cells
  • Imm (Immunogen: Listed application)
$680.09 View price
  • 100 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7318080
IL-10 Protein (His tag) IL10 · Protein Human Escherichia coli (E. coli)
  • CC (Cell Culture: Listed application)
$721.18 View price
  • 100 μg
  • 5 μg
  • 20 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669008
IL-10 Protein (AA 19-178) (TRX tag) IL10 · Protein Rat Escherichia coli (E. coli)
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669006
IL-10 Protein (AA 1-178) (His tag) IL10 · Protein Human HEK-293 Cells
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669005
IL-10 Protein (His tag) IL10 · Protein Mouse HEK-293 Cells
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7505765
IL-10 Protein (AA 1-178) (His tag) IL10 · Protein Rabbit HEK-293 Cells
  • Imm (Immunogen: Listed application)
$680.09 View price
  • 100 μg
  • 1 mg
  • 20 μg
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669011
IL-10 Protein (AA 19-178) (TRX tag) IL10 · Protein Human Escherichia coli (E. coli)
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669007
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Rat Escherichia coli (E. coli)
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669009
IL-10 Protein (AA 19-175) (GST tag) IL10 · Protein Pig Escherichia coli (E. coli)
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669004
IL-10 Protein (His tag) IL10 · Protein Pig Escherichia coli (E. coli)
  • CC (Cell Culture: Listed application)
$256.37 View price
  • 5 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669010
IL-10 Protein (AA 19-178) (His tag) IL10 · Protein Human Escherichia coli (E. coli)
  • Imm (Immunogen: Listed application)
$1,902.46 View price
  • 500 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7318100
IL-10 Protein (AA 19-178) IL10 · Protein Human HEK-293 Cells
  • BLI (Bio-Layer Interferometry: Listed application)
$423.29 View price
  • 50 μg
  • 10 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN5509243
IL-10 Protein IL10 · Protein Mouse CHO Cells
  • Func (Functional Studies: Listed application)
$930.00 View price
  • 20 μg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7387454
IL-10 Protein (AA 1-178) (His tag) IL10 · Protein Human Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$689.70 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
ABIN7387451
IL-10 Protein (His tag) IL10 · Protein Guinea Pig Escherichia coli (E. coli)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
$737.78 View price
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
Delivery in 13 to 17 Business Days Shipping to: United States
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Pig
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7387460
$1,039.24
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Chicken
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 %
Catalog No. ABIN7387448
$879.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Rhesus Monkey
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7414903
$785.85
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
Origin
Rat
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 80 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7321255
$474.65
Plus shipping costs $50.00
20 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN8056997
$680.09
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN8056998
$680.09
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • CC (Cell Culture: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 98 % as determined by reducing SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7318080
$721.18
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Rat
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669008
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669006
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669005
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Rabbit
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 80 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505765
$680.09
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669011
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Rat
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669007
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Pig
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669009
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • CC (Cell Culture: Listed application)
Origin
Pig
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 98 % as determined by reducing SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7669004
$256.37
Plus shipping costs $50.00
5 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Imm (Immunogen: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669010
$1,902.46
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • BLI (Bio-Layer Interferometry: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7318100
$423.29
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • Func (Functional Studies: Listed application)
Origin
Mouse
Host
CHO Cells
Protein Type
Recombinant
Purity
>95 % as determined by SDS-PAGE
Catalog No. ABIN5509243
$930.00
Plus shipping costs $50.00
20 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7387454
$689.70
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days
Protein
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
  • PC (Positive Control: Listed application)
Origin
Guinea Pig
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7387451
$737.78
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 17 Business Days

Latest Publications for our IL-10 Proteins

Phadnis-Moghe, Crawford, Kaminski: "Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 144, Issue 1, pp. 39-50, (2015) (PubMed).

Larson, Hübner, Torrero, Morris, Brankin, Swierczewski, Davies, Vonakis, Mitre: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).

Yang, Hirose, Takahashi, Kawakatsu, Takaiwa: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).

Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).

van der Vliet, Wang, Yue, Koon, Balk, Exley: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Schlaak, Schmitt, Hüls, Meyer zum Büschenfelde, Fleischer: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).

Feng, Tang, Chang, Wilson: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).

Howard, OGarra, Ishida, de Waal Malefyt, de Vries: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).

Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).

Aliases for IL-10 Proteins

interleukin 10 (IL10) Proteins
interleukin 10 (Il10) Proteins
CSIF Proteins
GVHDS Proteins
IL-10 Proteins
Il-10 Proteins
IL10A Proteins
IL10X Proteins
TGIF Proteins
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