anti-Rat (Rattus) Caspase 1 antibody for Immunocytochemistry

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase
  • caspase recruitment domain-containing protein 16
  • caspase 4
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Caspase1
  • LOC5564196
  • LOC451519
Reactivity
Human, Mouse (Murine), Rat (Rattus)
258
95
74
8
2
2
2
1
1
1
1
1
1
Host
Rabbit
249
37
8
2
Clonality
Polyclonal
Conjugate
This Caspase 1 antibody is un-conjugated
23
16
8
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
266
160
117
76
32
25
17
15
7
5
3
3
1
Supplier
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Catalog No. ABIN6260470
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
10 ABIN1174809 ICC IHC WB Rabbit IgG AA 119-296 Log in to see Polyclonal 0
1 ABIN200369 ICC IP WB Rabbit AA 225-242 Log in to see Polyclonal 0
1 ABIN2591791 ICC IF WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN2886302 ICC WB Rabbit AA 327-372 Log in to see Polyclonal 0

General

Antigen Caspase 1 (CASP1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(258), (95), (74), (8), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(249), (37), (8), (2)
Clonality
Polyclonal
Conjugate This Caspase 1 antibody is un-conjugated
(23), (16), (8), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(266), (160), (117), (76), (32), (25), (17), (15), (7), (5), (3), (3), (1)
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Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling Images
Specificity CASP1 Antibody detects endogenous levels of total CASP1
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human CASP1
Isotype IgG
Plasmids, Primers & others

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CASP1 (CASP1 Antibody Abstract)
Background

Description: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive (PubMed:28314590).

Gene: CASP1

Molecular Weight 45kDa
Gene ID 834
UniProt P29466
Pathways Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 1 (CASP1) antibody (ABIN6260470) Western blot analysis of Mouse Spleen tissue lysate, using CASP1 Antibody. The lane o...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Caspase 1 (CASP1) antibody (ABIN6260470) ABIN6276418 staining 293 cells by IF/ICC. The sample were fixed with PFA and permeabi...
Immunohistochemistry (IHC) image for anti-Caspase 1 (CASP1) antibody (ABIN6260470) ABIN6276418 at 1/100 staining Mouse brain tissue by IHC-P. The sample was formaldehyd...