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anti-Human ACTR1A Antibodies:
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Human Polyclonal ACTR1A Primary Antibody for ELISA, WB - ABIN250222
Lees-Miller, Helfman, Schroer: A vertebrate actin-related protein is a component of a multisubunit complex involved in microtubule-based vesicle motility. in Nature 1992
ARP1 interacted with two regions of the FVII 5' flanking region, the hepatic nuclear factor 4 binding region and the nuclear hormone response region, indicating a role for ARP1 in transcriptional modulation of the FVII gene.
point mutation observed by transcriptome sequencing of malignant pleural mesothelioma tumors
Beta-III spectrin mutation L253P interferes with binding to Arp1 and protein trafficking from the Golgi.
Arp1 can directly bind any protein besides another Arp.
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
, centrosome-associated actin homolog
, ARP1 actin-related protein 1 homolog A, centractin alpha
, Arp1 centractin alpha
, Arp1 contractin alpha
, actin-related protein 1 alpha
, actin-related protein 1 homolog A
, ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
, ARP1 actin-related protein 1 homolog A, centractin alpha-like