We are preparing the requested document. Please wait, this may take a while...!
|Antigen||Insulin Receptor (INSR) Antibodies|
|Epitope||AA 59-75, N-Term Alternatives|
|Reactivity||Dog (Canine), Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Insulin Receptor antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-Insulin Receptor AntibodyTarget Details Insulin Receptor Application Details Handling Images
|Purpose||Rabbit IgG polyclonal antibody for Insulin receptor(INSR) detection. Tested with WB, IHC-P in Human,Mouse,Rat,Dog.|
Rabbit IgG polyclonal antibody for Insulin receptor(INSR) detection. Tested with WB, IHC-P in Human,Mouse,Rat,Dog.
Gene Name: insulin receptor
Protein Name: Insulin receptor(IR)
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the N-terminus of human Insulin Receptor alpha(59-75aa HLQILLMFKTRPEDFRD), identical to the related rat and mouse sequences.|
Target Details Insulin ReceptorProduct Details anti-Insulin Receptor Antibody Application Details Handling Images back to top
|Alternative Name||INSR (INSR Antibody Abstract)|
Insulin receptor is a tetramer of 2 alpha and 2 beta subunits. The alpha and beta subunits are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. The insulin receptor has an intrinsic tyrosine kinase activity that is essential for signal transduction. A mutant insulin receptor gene lacking almost the entire kinase domain has been identified in an individual with type A insulin resistance and acanthosis nigricans.
Synonyms: CD220 antibody|CD220 antigen antibody|HHF5 antibody|HIR A antibody|INSR alpha antibody|INSR antibody|Insulin receptor antibody|Insulin receptor subunit alpha antibody|IR antibody
|Pathways||NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity|
Application DetailsProduct Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Dog, Rat, Predicted Species: Human, Mouse
|Restrictions||For Research Use only|
HandlingProduct Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.|
|Preservative||Sodium azide, Thimerosal (Merthiolate)|
|Precaution of Use||This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.