anti-Baboon NGFR antibody for Immunohistochemistry

Recommended NGFR Antibody (supplied by: Log in to see )

Antigen
Nerve Growth Factor Receptor (NGFR) Antibodies
  • ngfr
  • wu:fb38c02
  • wu:fc10h01
  • CD271
  • Gp80-LNGFR
  • TNFRSF16
  • p75(NTR)
  • p75NTR
  • LNGFR
  • RNNGFRR
  • Tnfrsf16
  • p75
  • NRH1b
  • fullback
  • nrh1
  • p75ntr
  • tnfrsf16
  • p75NGFR
  • nerve growth factor receptor
  • neurotrophin receptor associated death domain
  • nerve growth factor receptor S homeolog
  • nerve growth factor receptor (TNFR superfamily, member 16)
  • NGFR
  • nradd
  • Ngfr
  • ngfr.S
Reactivity
Baboon, Cat (Feline), Ferret, Human, Monkey, Rabbit
271
109
98
29
27
25
23
12
10
10
8
5
5
5
3
3
2
2
2
1
Host
Mouse
138
125
33
4
1
Clonality
Monoclonal
Conjugate
This NGFR antibody is un-conjugated
19
15
15
14
5
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
203
111
110
80
67
57
40
32
15
14
13
6
6
6
4
4
3
1
1
1
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Catalog No. ABIN3025048
$ 361.90
Plus shipping costs $45.00

General

Antigen Nerve Growth Factor Receptor (NGFR) Antibodies
Reactivity Baboon, Cat (Feline), Ferret, Human, Monkey, Rabbit
(271), (109), (98), (29), (27), (25), (23), (12), (10), (10), (8), (5), (5), (5), (3), (3), (2), (2), (2), (1)
Host Mouse
(138), (125), (33), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This NGFR antibody is un-conjugated
(19), (15), (15), (14), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC)
(203), (111), (110), (80), (67), (57), (40), (32), (15), (14), (13), (6), (6), (6), (4), (4), (3), (1), (1), (1)
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Product Details anti-NGFR Antibody

Target Details NGFR Application Details Handling Images
No Cross-Reactivity Mouse (Murine), Rat (Rattus)
Characteristics It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Purification Protein G affinity chromatography
Immunogen NGFR from A875 melanoma cells was used as the immunogen for the p75NTR antibody.
Clone NGFR5
Isotype IgG1, kappa

Target Details NGFR

Product Details anti-NGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name p75NTR (NGFR Antibody Abstract)
Background It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-NGFR Antibody Target Details NGFR Handling Images back to top
Application Notes Optimal dilution of the p75NTR antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted format : incubate for 30 min at RT (2)

Restrictions For Research Use only

Handling

Product Details anti-NGFR Antibody Target Details NGFR Application Details Images back to top
Format Liquid
Buffer Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store the p75NTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).