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|Antigen||Nerve Growth Factor Receptor (NGFR) Antibodies|
|Epitope||AA 397-414, C-Term Alternatives|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This NGFR antibody is un-conjugated Alternatives|
Western Blotting (WB)
|2 references available|
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Product Details anti-NGFR AntibodyTarget Details NGFR Application Details Handling References for anti-NGFR antibody (ABIN3042534) Images
|Purpose||Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 16(NGFR) detection. Tested with WB in Human,Mouse,Rat.|
Predicted Cross Reactivity: rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 16(NGFR) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nerve growth factor receptor
Protein Name: Tumor necrosis factor receptor superfamily member 16
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human p75 NGF Receptor(397-414aa TLDALLAALRRIQRADLV), different from the related mouse and rat sequences by one amino acid.|
Target Details NGFRProduct Details anti-NGFR Antibody Application Details Handling References for anti-NGFR antibody (ABIN3042534) Images back to top
|Alternative Name||NGFR (NGFR Antibody Abstract)|
The Low-Affinity Nerve Growth Factor Receptor(also called the NGFR or p75 neurotrophin receptor) is one of the two receptor types for the neurotrophins, a family of protein growth factors that stimulate neuronal cells to survive and differentiate. It is mapped to 17q21.33. Overexpression of NGFR was also found to activate the SM pathway. NGFR is a receptor for rabies virus, and it is also a coreceptor for the NOGO receptor for MAG signaling. This gene is a signaling partner for EPHAs and the EPHA/NGFR complex reverse signals can mediate axon repulsion required for guidance and mapping. NGFR is involved in activity-dependent synaptic plasticity. It has been shown to interact with PRKACB, FSCN1, TRAF4, Nerve growth factor, TRAF2, NDN, NGFRAP1 and MAGEH1.
Synonyms: CD271 antibody|CD271 antigen antibody|Gp80 LNGFR antibody|Gp80-LNGFR antibody|Low affinity nerve growth factor receptor antibody|Low affinity neurotrophin receptor p75NTR antibody|Low affinity neurotrophin receptor p75NTR antibody|Low-affinity nerve growth factor receptor antibody|Nerve growth factor receptor antibody|Nerve growth factor receptor TNFR superfamily member 16 antibody|NGF receptor antibody|NGF receptor antibody|Ngfr antibody|p75 ICD antibody|p75 ICD antibody|p75 Neurotrophin receptor antibody|p75 NTR antibody|p75(NTR) antibody|p75NTR antibody|TNFR Superfamily Member 16 antibody|TNFRSF16 antibody|TNR16_HUMAN antibody|Tumor necrosis factor receptor superfamily member 16 antibody
|Pathways||NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding|
Application DetailsProduct Details anti-NGFR Antibody Target Details NGFR Handling References for anti-NGFR antibody (ABIN3042534) Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Predicted Species: Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-NGFR Antibody Target Details NGFR Application Details References for anti-NGFR antibody (ABIN3042534) Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.|
|Preservative||Thimerosal (Merthiolate), Sodium azide|
|Precaution of Use||This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-NGFR antibody (ABIN3042534)Product Details anti-NGFR Antibody Target Details NGFR Application Details Handling Images back to top
|Product cited in:||
Fan, Shen, Zhang, Zuo, Lu, Wu, Xie, Dong, Zhang: "Control of olfactory ensheathing cell behaviors by electrospun silk fibroin fibers." in: Cell transplantation, Vol. 22 Suppl 1, pp. S39-50, 2013
Shen, Qian, Zhang, Zuo, Lu, Fan, Zhang, Zhang, Zhou: "Guidance of olfactory ensheathing cell growth and migration on electrospun silk fibroin scaffolds." in: Cell transplantation, Vol. 19, Issue 2, pp. 147-57, 2010
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