anti-Goat TNFRSF1A antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TNFRSF1A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
  • CD120a
  • FPF
  • MS5
  • TBP1
  • TNF-R
  • TNF-R-I
  • TNF-R55
  • TNFAR
  • TNFR1
  • TNFR1-d2
  • TNFR55
  • TNFR60
  • p55
  • p55-R
  • p60
  • TNF-R1
  • TNF-alphaR1
  • TNFRI
  • TNFRp55
  • TNFalpha-R1
  • Tnfr-2
  • Tnfr1
  • fpf
  • tbp1
  • p55-r
  • tnf-r
  • tnfar
  • tnfr1
  • cd120a
  • tnfr55
  • tnfr60
  • xtnfr1
  • wu:fj65b10
  • zgc:85914
  • TNFR I
  • TNFRSF1A
  • TNF receptor superfamily member 1A
  • tumor necrosis factor receptor superfamily, member 1a
  • TNF receptor superfamily member 1A S homeolog
  • TNFRSF1A
  • Tnfrsf1a
  • tnfrsf1a.S
  • tnfrsf1a
Epitope
AA 195-211, N-Term
51
37
24
19
15
14
12
11
7
6
6
5
5
5
5
5
4
4
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Goat, Human, Mouse (Murine), Rat (Rattus)
381
182
109
61
55
52
47
16
14
9
9
8
8
4
3
2
1
Host
Rabbit
262
139
22
17
16
15
1
Clonality
Polyclonal
Conjugate
This TNFRSF1A antibody is un-conjugated
33
28
27
16
12
9
8
7
6
6
6
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
301
184
154
112
104
82
46
44
31
23
22
17
13
7
7
7
7
4
3
2
2
2
2
1
1
1
1
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Catalog No. ABIN1105799
$ 379.50
Plus shipping costs $45.00

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
Epitope AA 195-211, N-Term
(51), (37), (24), (19), (15), (14), (12), (11), (7), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Goat, Human, Mouse (Murine), Rat (Rattus)
(381), (182), (109), (61), (55), (52), (47), (16), (14), (9), (9), (8), (8), (4), (3), (2), (1)
Host Rabbit
(262), (139), (22), (17), (16), (15), (1)
Clonality
Polyclonal
Conjugate This TNFRSF1A antibody is un-conjugated
(33), (28), (27), (16), (12), (9), (8), (7), (6), (6), (6), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(301), (184), (154), (112), (104), (82), (46), (44), (31), (23), (22), (17), (13), (7), (7), (7), (7), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
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Product Details anti-TNFRSF1A Antibody

Target Details TNFRSF1A Application Details Handling Images
Specificity This antibody detects CD120a / TNFR1 (195-211). No cross reactivity with other proteins.
Cross-Reactivity (Details) Species reactivity (tested):Goat, human, mouse, rat
Purification Immunogen affinity purified
Immunogen A synthetic peptide corresponding to a sequence at the N-terminal of human TNFR1 .Remarks: Sequence id different to the related rat sequence by a single amino acid.
Isotype IgG

Target Details TNFRSF1A

Product Details anti-TNFRSF1A Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD120a / TNFR1 (TNFRSF1A Antibody Abstract)
Background Tumor necrosis factor receptor 1(TNFR1), a potent cytokine, elicits a broad spectrum of biologic responses which are mediated by binding to a cell surface receptor. Its gene is located on 12p13.2. The coding region and the 3-prime untranslated region of TNFR1 are distributed over 10 exons. There are 2 different proteins that serve as major receptors for TNF-alpha, one associated with myeloid cells and one associated with epithelial cells. Additionally, TNFR1 associates with the MADD protein through a death domain-death domain interaction. MADD provides a physical link between TNFR1 and the induction of mitogen-activated protein (MAP) kinase (e.g., ERK2) activation and arachidonic acid release. TNFR1-induced apoptosis involves 2 sequential signaling complexes. Complex I, the initial plasma membrane-bound complex, consists of TNFR1, the adaptor TRADD, the kinase RIP1, and TRAF2 and rapidly signals activation of NF-kappa-B. In a second step, TRADD and RIP1 associate with FADD and caspase-8, forming a cytoplasmic complex, complex II.Synonyms: TNF-R1, TNF-RI, TNFR-I, Tnfrsf1a, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I, p55, p60
Gene ID 7132
NCBI Accession NP_001056
UniProt P19438
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C

Application Details

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Images back to top
Reconstitution 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Preservative Sodium azide, Thimerosal (Merthiolate)
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.