anti-Human TNFRSF1A antibody for Functional Studies

Recommended TNFRSF1A Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
  • CD120a
  • FPF
  • MS5
  • TBP1
  • TNF-R
  • TNF-R-I
  • TNF-R55
  • TNFAR
  • TNFR1
  • TNFR1-d2
  • TNFR55
  • TNFR60
  • p55
  • p55-R
  • p60
  • TNF-R1
  • TNF-alphaR1
  • TNFRI
  • TNFRp55
  • TNFalpha-R1
  • Tnfr-2
  • Tnfr1
  • fpf
  • tbp1
  • p55-r
  • tnf-r
  • tnfar
  • tnfr1
  • cd120a
  • tnfr55
  • tnfr60
  • xtnfr1
  • wu:fj65b10
  • zgc:85914
  • TNFR I
  • TNFRSF1A
  • TNFA
  • cTNF
  • TNF receptor superfamily member 1A
  • tumor necrosis factor receptor superfamily, member 1a
  • TNF receptor superfamily member 1A S homeolog
  • tumor necrosis factor
  • TNFRSF1A
  • Tnfrsf1a
  • tnfrsf1a.S
  • tnfrsf1a
  • TNF
Reactivity
Human
370
204
129
76
71
68
63
14
11
7
7
6
6
3
2
1
1
1
Host
Mouse
277
116
22
17
15
14
1
Clonality
Monoclonal
Conjugate
This TNFRSF1A antibody is un-conjugated
35
29
29
17
12
10
8
6
5
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
297
173
168
136
118
78
44
43
31
28
23
18
13
11
7
6
5
4
3
2
2
2
1
1
1
1
Options
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Catalog No. ABIN1981872
$ 343.07
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
17.311565 ABIN2749013 Func IHC (f) FACS IP IHC (p) Mouse IgG2a Log in to see H398 2
12.811565 ABIN5711607 FACS Func IHC (f) IHC (p) IP PE Mouse IgG2a Log in to see H398 0
5.5 ABIN1105792 Func EIA IHC (fro) FACS IP WB Mouse IgG2a Log in to see H398 5
1 ABIN111939 Func FACS IHC (fro) WB Mouse IgG1 Log in to see htr9 6
1 ABIN299012 FACS Func IHC IHC (fro) IP Mouse IgG2a Log in to see H398 0
1 ABIN116277 EIA Func WB Rabbit Log in to see Polyclonal 0
1 ABIN116278 EIA Func WB Rabbit Log in to see Polyclonal 0
1 ABIN3199428 FACS Func IHC IP Mouse IgG2a full length Log in to see H398 0
1 ABIN3199429 FACS Func IHC IP Mouse IgG2a full length Log in to see H398 0
1 ABIN1105787 Func EIA IHC (fro) Mouse IgG1 Log in to see MR1-2 1
1 ABIN5540101 FACS Func IHC (fro) IHC (p) IP Mouse IgG2a Log in to see H398 0

General

Antigen Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies
Reactivity Human
(370), (204), (129), (76), (71), (68), (63), (14), (11), (7), (7), (6), (6), (3), (2), (1), (1), (1)
Host Mouse
(277), (116), (22), (17), (15), (14), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TNFRSF1A antibody is un-conjugated
(35), (29), (29), (17), (12), (10), (8), (6), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(297), (173), (168), (136), (118), (78), (44), (43), (31), (28), (23), (18), (13), (11), (7), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-TNFRSF1A Antibody

Target Details TNFRSF1A Application Details Handling References for anti-TNFRSF1A antibody (ABIN1981872) Images
Specificity The mouse monoclonal antibody H398 recognizes the extracellular domain of CD120a, a 55 kDa receptor for tumor necrosis factor. The antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta.
Cross-Reactivity (Details) Human
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Immunogen Recombinant full length human CD120a
Clone H398
Isotype IgG2a
Plasmids, Primers & others

Target Details TNFRSF1A

Product Details anti-TNFRSF1A Antibody Application Details Handling References for anti-TNFRSF1A antibody (ABIN1981872) Images back to top
Antigen
Alternative Name CD120a (TNFRSF1A Antibody Abstract)
Background CD120a / TNF R1, also known as TNFR55 or TNFRSF1A, is a 55 kDa receptor for tumor necrosis factor alpha and it is expressed in most tissues. By binding its trimeric ligand the CD120a protein forms trimers and the conformation change leads to dissociation of the inhibitory factor SODD from its intracellular death domain and in formation of signaling platform. CD120a can mediate apoptosis, and function as a regulator of inflammation. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
Gene ID 7132
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C

Application Details

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling References for anti-TNFRSF1A antibody (ABIN1981872) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details References for anti-TNFRSF1A antibody (ABIN1981872) Images back to top
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze. Do not use after expiration date stamped on vial label.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

References for anti-TNFRSF1A antibody (ABIN1981872)

Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Handling Images back to top
Product cited in:

Baker, Pettitt, Slupsky, Chen, Glenn, Zuzel, Cawley: "Response of hairy cells to IFN-alpha involves induction of apoptosis through autocrine TNF-alpha and protection by adhesion." in: Blood, Vol. 100, Issue 2, pp. 647-53, 2002