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|Antigen||Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) Antibodies|
|Epitope||AA 1-212 Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This TNFRSF1A antibody is un-conjugated Alternatives|
|2 references available|
|Supplier||Log in to see|
Product Details anti-TNFRSF1A AntibodyTarget Details TNFRSF1A Application Details Handling References for anti-TNFRSF1A antibody (ABIN2001043) Images
|Specificity||Mouse TNFR1 / CD120a / TNFRSF1A|
|Characteristics||Produced in rabbits immunized with purified, recombinant Mouse TNFR1 / CD120a / TNFRSF1A (rM TNFR1 / CD120a / TNFRSF1A, ABIN2007898 NP_035739.2, Met 1-Ala 212,. TNFR1 / CD120a / TNFRSF1A specific IgG was purified by Mouse TNFR1 / CD120a / TNFRSF1A affinity chromatography.|
|Purification||purified by affinity chromatography|
|Sterility||0.2 μm filtered|
|Immunogen||Recombinant Mouse TNFR1 / CD120a / TNFRSF1A protein (ABIN2007898)|
|Plasmids, Primers & others|
Target Details TNFRSF1AProduct Details anti-TNFRSF1A Antibody Application Details Handling References for anti-TNFRSF1A antibody (ABIN2001043) Images back to top
|Alternative Name||TNFRSF1A (TNFRSF1A Antibody Abstract)|
|Background||The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF- κB, mediate apoptosis, and regulate inflammation processes.|
|Pathways||NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Hepatitis C|
Application DetailsProduct Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Handling References for anti-TNFRSF1A antibody (ABIN2001043) Images back to top
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse TNFRSF1A. The detection limit for Mouse TNFRSF1A is approximately 0.00245 ng/well.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details References for anti-TNFRSF1A antibody (ABIN2001043) Images back to top
|Buffer||0.2 μm filtered solution in PBS with 5 % trehalose|
|Handling Advice||Avoid repeated freeze-thaw cycles.|
|Storage||4 °C,-20 °C,-80 °C|
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
|Expiry Date||12 months|
References for anti-TNFRSF1A antibody (ABIN2001043)Product Details anti-TNFRSF1A Antibody Target Details TNFRSF1A Application Details Handling Images back to top
Seto: "Histone modifications." in: Methods (San Diego, Calif.), Vol. 31, Issue 1, pp. 1-2, 2003
Cottin, Doan, Riches: "Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 8, pp. 4095-102, 2002