|Antigen||Jagged 2 (JAG2) Antibodies|
|Epitope||AA 111-128 Alternatives|
|Reactivity||Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This JAG2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA)
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Product Details anti-JAG2 AntibodyTarget Details JAG2 Application Details Handling Images
Species reactivity (expected):Rat.
Species reactivity (tested):Mouse.
|Immunogen||Synthetic peptide corresponding to amino acids 111-128 of Mouse Jagged-2|
|Plasmids, Primers & others|
Target Details JAG2Product Details anti-JAG2 Antibody Application Details Handling Images back to top
|Alternative Name||Jagged-2 / JAG2 (JAG2 Antibody Abstract)|
|Background||Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.Synonyms: hJ2|
|Pathways||Notch Signaling, Sensory Perception of Sound|
Application DetailsProduct Details anti-JAG2 Antibody Target Details JAG2 Handling Images back to top
ELISA: 1/20000 - 1/90000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-JAG2 Antibody Target Details JAG2 Application Details Images back to top
|Concentration||0.9 mg/mL (by UV absorbance at 280 nm)|
|Buffer||0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|