anti-Horse (Equine) Progesterone Receptor antibody for Western Blotting

Recommended Progesterone Receptor Antibody (supplied by: Log in to see )

Antigen
Progesterone Receptor (PGR) Antibodies
  • NR3C3
  • PR
  • 9930019P03Rik
  • BB114106
  • ENSMUSG00000074510
  • PR-A
  • PR-B
  • XPR-1
  • pgr
  • xpr-2
  • LOC443444
  • PGR
  • pg
  • pr
  • gb:dq017620
  • progesterone receptor
  • progesterone receptor L homeolog
  • PGR
  • Pgr
  • pgr.L
  • pgr
Reactivity
Horse (Equine), Human, Pig (Porcine)
704
115
109
38
26
22
19
17
15
15
12
10
6
4
2
1
1
1
1
1
Host
Mouse
392
338
3
1
Clonality
Monoclonal
Conjugate
This Progesterone Receptor antibody is un-conjugated
25
22
17
14
14
12
8
8
6
6
6
6
6
6
6
5
5
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
550
221
188
183
129
74
67
54
52
36
28
19
9
3
2
2
1
1
1
1
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Catalog No. ABIN264434
$ 654.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN341160 IP WB Mouse IgG1 AA 919-933 Log in to see C262 0
1 ABIN385222 IF IHC IHC (p) IP WB Mouse IgG1, kappa Log in to see hPRa 2 0
1 ABIN1103572 IF IHC IHC (p) IP WB Mouse Log in to see hPRa 2-hPRa 3 0
1 ABIN233672 IF IHC IHC (p) IP WB Mouse IgG1, kappa Log in to see 0

General

Antigen Progesterone Receptor (PGR) Antibodies
Reactivity Horse (Equine), Human, Pig (Porcine)
(704), (115), (109), (38), (26), (22), (19), (17), (15), (15), (12), (10), (6), (4), (2), (1), (1), (1), (1), (1)
Host Mouse
(392), (338), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Progesterone Receptor antibody is un-conjugated
(25), (22), (17), (14), (14), (12), (8), (8), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(550), (221), (188), (183), (129), (74), (67), (54), (52), (36), (28), (19), (9), (3), (2), (2), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-Progesterone Receptor Antibody

Target Details Progesterone Receptor Application Details Handling References for anti-Progesterone Receptor antibody (ABIN264434) Images
Specificity This antibody equally recognizes two proteins: 116 kDa (triplet) and 81 kDa (singlet), identified as the hormone-binding high (B) and low (A) MW forms of human PgR.
Characteristics Synonyms: PR, PGR, NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3
Purification Purified
Immunogen Hybridoma produced by the fusion of splenocytes from RBF/DN mice immunized with PgRfrom a human endometrial carcinoma (EnCa 101) grown in athymic mice and mousemyeloma HL-1 Friendly cells. Genename: PGR
Clone HPRa2-hPRa3
Isotype IgG
Plasmids, Primers & others

Target Details Progesterone Receptor

Product Details anti-Progesterone Receptor Antibody Application Details Handling References for anti-Progesterone Receptor antibody (ABIN264434) Images back to top
Antigen
Alternative Name Progesterone Receptor (PGR Antibody Abstract)
Background Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. This antibody is excellent for immunohistochemical staining of formalin/paraffin tissues.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
Gene ID 5241
UniProt P06401
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration

Application Details

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Handling References for anti-Progesterone Receptor antibody (ABIN264434) Images back to top
Application Notes Western Blot (1 μg/mL). Immunoprecipitation (2 g/mg of protein lysate). Immunohistochemistry (Paraffin and Frozen sections, 2-4 μg/mL). Immunofluorescense. Positive Control: T47D or breast carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Application Details References for anti-Progesterone Receptor antibody (ABIN264434) Images back to top
Buffer PBS containing 0.08 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch
Expiry Date 12 months

References for anti-Progesterone Receptor antibody (ABIN264434)

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Application Details Handling Images back to top
Background publications

Satyaswaroop: "Development of a preclinical model for hormonal therapy of human endometrial carcinomas." in: Annals of medicine, Vol. 25, Issue 2, pp. 105-11, 1993

Satyaswaroop, Clarke, Zaino, Mortel: "Apparent resistance in human endometrial carcinoma during combination treatment with tamoxifen and progestin may result from desensitization following downregulation of tumor progesterone receptor." in: Cancer letters, Vol. 62, Issue 2, pp. 107-14, 1992

Clarke, Graham, Roman, Sutherland: "Direct transcriptional regulation of the progesterone receptor by retinoic acid diminishes progestin responsiveness in the breast cancer cell line T-47D." in: The Journal of biological chemistry, Vol. 266, Issue 28, pp. 18969-75, 1991

Schneider, Ramachandran, Satyaswaroop, Shyamala: "Murine progesterone receptor exists predominantly as the 83-kilodalton 'A' form." in: The Journal of steroid biochemistry and molecular biology, Vol. 38, Issue 3, pp. 285-91, 1991

Mortel, Zaino, Satyaswaroop: "Designing a schedule of progestin administration in the control of endometrial carcinoma growth in the nude mouse model." in: American journal of obstetrics and gynecology, Vol. 162, Issue 4, pp. 928-34; discussion 934-6, 1990

Clarke, Roman, Graham, Koga, Sutherland: "Progesterone receptor regulation by retinoic acid in the human breast cancer cell line T-47D." in: The Journal of biological chemistry, Vol. 265, Issue 21, pp. 12694-700, 1990

Images

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Application Details Handling References for anti-Progesterone Receptor antibody (ABIN264434) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Progesterone Receptor (PGR) antibody (ABIN264434) anti-Progesterone Receptor (PGR) antibody